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Melt extrusion with poorly soluble drugs–An integrated review
Over the last few decades, hot melt extrusion (HME) has emerged as a successful
technology for a broad spectrum of applications in the pharmaceutical industry. As indicated …
technology for a broad spectrum of applications in the pharmaceutical industry. As indicated …
[HTML][HTML] Eudragit®: A Versatile Family of Polymers for Hot Melt Extrusion and 3D Printing Processes in Pharmaceutics
Eudragit® polymers are polymethacrylates highly used in pharmaceutics for the
development of modified drug delivery systems. They are widely known due to their …
development of modified drug delivery systems. They are widely known due to their …
Coupling 3D printing with hot-melt extrusion to produce controlled-release tablets
The main objective of this work was to explore the potential of coupling fused deposition
modeling in three-dimensional (3D) printing with hot-melt extrusion (HME) technology to …
modeling in three-dimensional (3D) printing with hot-melt extrusion (HME) technology to …
[HTML][HTML] Novel gastroretentive floating pulsatile drug delivery system produced via hot-melt extrusion and fused deposition modeling 3D printing
This study was performed to develop novel core-shell gastroretentive floating pulsatile drug
delivery systems using a hot-melt extrusion-paired fused deposition modeling (FDM) 3D …
delivery systems using a hot-melt extrusion-paired fused deposition modeling (FDM) 3D …
Hydroxypropyl methylcellulose-based controlled release dosage by melt extrusion and 3D printing: Structure and drug release correlation
The objective of this study was to develop a new approach for fabrication of zero order
release of active pharmaceutical ingredients (APIs) using hot-melt extrusion (HME) and 3D …
release of active pharmaceutical ingredients (APIs) using hot-melt extrusion (HME) and 3D …
A systematic and robust assessment of hot-melt extrusion-based amorphous solid dispersions: Theoretical prediction to practical implementation
Amorphous solid dispersions (ASDs) have gained attention as a formulation strategy in
recent years, with the potential to improve the apparent solubility and, hence, the oral …
recent years, with the potential to improve the apparent solubility and, hence, the oral …
Hot melt extrusion paired fused deposition modeling 3D printing to develop hydroxypropyl cellulose based floating tablets of cinnarizine
Three-dimensional printing could serve as a platform to fabricate individualized medicines
and complex-structured solid dosage forms. Herein, hot melt extrusion was coupled with 3D …
and complex-structured solid dosage forms. Herein, hot melt extrusion was coupled with 3D …
[HTML][HTML] Hot-melt extrusion in the pharmaceutical industry: toward filing a new drug application
MF Simões, RMA Pinto, S Simões - Drug Discovery Today, 2019 - Elsevier
The pharmaceutical development of amorphous solid dispersions (ASDs) by hot-melt
extrusion (HME) is briefly reviewed. A systematic step-by-step approach is presented, where …
extrusion (HME) is briefly reviewed. A systematic step-by-step approach is presented, where …
Systematic screening of pharmaceutical polymers for hot melt extrusion processing: A comprehensive review
Pharmaceutical research, whether industrial or academic, has attempted to adopt
approaches most efficient for the development of innovations. With the abundance of …
approaches most efficient for the development of innovations. With the abundance of …
Hot-melt extrusion: Highlighting recent advances in pharmaceutical applications
Hot-melt extrusion (HME) has emerged as a pioneering manufacturing technology for
pharmaceutical industries, and the utilization is overgrowing due to its unit operation, cost …
pharmaceutical industries, and the utilization is overgrowing due to its unit operation, cost …