The aim of evidence-based medicine is to improve the quality of health care by integrating
the best research evidence with clinical expertise and patient values. Evidence-based …

Importance Barrett esophagus, a complication of gastroesophageal reflux disease (GERD),
predisposes patients to esophageal adenocarcinoma, a tumor that has increased in …

Barrett's esophagus (BE) is a common condition associated with chronic gastroesophageal
reflux disease. BE is the only known precursor to esophageal adenocarcinoma, a highly …

The guidelines for the diagnosis, surveillance and therapy of Barrett's esophagus were
originally published by the American College of Gastroenterology in 1998 and updated in …

Background and aims Acid-suppressive medications, particularly proton pump inhibitors
(PPIs), may decrease the risk of oesophageal adenocarcinoma (OAC) in patients with …

The public health importance of Barrett's oesophagus lies in its association with
oesophageal adenocarcinoma. The incidence of oesophageal adenocarcinoma has risen at …

Background & Aims: The diagnosis and management of Barrett's esophagus (BE) are
controversial. We conducted a critical review of the literature in BE to provide guidance on …

A 55-year-old man has had frequent heartburn for more than 10 years. Endoscopy reveals
columnar epithelium lining the distal 5 cm of the esophagus. Biopsy specimens show …

BACKGROUND & AIMS: Acid exposure contributes to the development of Barrett's
esophagus (BE) and its progression toward esophageal adenocarcinoma. Patients with BE …

METHODS: We analyzed prospectively collected data by a single endoscopist on patients
with BE in a VA (Veterans Affairs) setting over a 20-yr time period (1981–2000). A …