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Cell death pathways in ischemic stroke and targeted pharmacotherapy
Ischemic stroke is one of the significant causes of morbidity and mortality, affecting millions
of people across the globe. Cell injury in the infarct region is an inevitable consequence of …
of people across the globe. Cell injury in the infarct region is an inevitable consequence of …
Age and sex are critical factors in ischemic stroke pathology
Ischemic stroke is a devastating brain injury resulting in high mortality and substantial loss of
function. Understanding the pathophysiology of ischemic stroke risk, mortality, and functional …
function. Understanding the pathophysiology of ischemic stroke risk, mortality, and functional …
Twenty-year change in severity and outcome of ischemic and hemorrhagic strokes
K Toyoda, S Yoshimura, M Nakai, M Koga… - JAMA …, 2022 - jamanetwork.com
Importance Whether recent changes in demographic characteristics and therapeutic
technologies have altered stroke outcomes remains unknown. Objective To determine …
technologies have altered stroke outcomes remains unknown. Objective To determine …
Sex differences in stroke: challenges and opportunities
Biologic sex influences many variables that are important to brain health in general, and to
stroke or cerebral ischemia in particular, such as general health status, cerebrovascular …
stroke or cerebral ischemia in particular, such as general health status, cerebrovascular …
State of the science in women's cardiovascular disease: a Canadian perspective on the influence of sex and gender
Cardiovascular disease (CVD) is the leading cause of premature death for women in
Canada. 1 Although it has long been recognized that estrogen impacts vascular responses …
Canada. 1 Although it has long been recognized that estrogen impacts vascular responses …
NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia
Diabetes increases the risk and worsens the progression of cognitive impairment via the
greater occurrence of small vessel disease and stroke. Yet, the underlying mechanisms are …
greater occurrence of small vessel disease and stroke. Yet, the underlying mechanisms are …
Stroke in women—from evidence to inequalities
Stroke is the second largest cause of disability-adjusted life-years lost worldwide. The
prevalence of stroke in women is predicted to rise rapidly, owing to the increasing average …
prevalence of stroke in women is predicted to rise rapidly, owing to the increasing average …
[HTML][HTML] Functional neurological disorder is a feminist issue
Functional neurological disorder (FND) is a common and disabling disorder, often
misunderstood by clinicians. Although viewed sceptically by some, FND is a diagnosis that …
misunderstood by clinicians. Although viewed sceptically by some, FND is a diagnosis that …
Toward a better understanding of sex-and gender-related differences in endovascular stroke treatment: a scientific statement from the American Heart Association …
There are many unknowns when it comes to the role of sex in the pathophysiology and
management of acute ischemic stroke. This is particularly true for endovascular treatment …
management of acute ischemic stroke. This is particularly true for endovascular treatment …
Incidence, risk factors, prognosis, and health-related quality of life after stroke in a low-resource community in Chile (ÑANDU): a prospective population-based study
Background Stroke is a leading cause of disability and death worldwide. The best estimates
of local, national, and global burden of stroke are derived from prospective population …
of local, national, and global burden of stroke are derived from prospective population …