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Paracrine mechanisms of mesenchymal stem cells in tissue repair
M Gnecchi, P Danieli, G Malpasso… - Mesenchymal Stem Cells …, 2016 - Springer
Tissue regeneration from transplanted mesenchymal stromal cells (MSC) either through
transdifferentiation or cell fusion was originally proposed as the principal mechanism …
transdifferentiation or cell fusion was originally proposed as the principal mechanism …
Trophic effects of mesenchymal stem cells in tissue regeneration
Mesenchymal stem cells (MSCs) are considered to hold great therapeutic value for cell-
based therapy and for tissue regeneration in particular. Recent evidence indicates that the …
based therapy and for tissue regeneration in particular. Recent evidence indicates that the …
[HTML][HTML] Therapeutic properties of mesenchymal stromal/stem cells: the need of cell priming for cell-free therapies in regenerative medicine
Mesenchymal stromal/stem cells (MSCs) are multipotent adult stem cells that support
homeostasis during tissue regeneration. In the last decade, cell therapies based on the use …
homeostasis during tissue regeneration. In the last decade, cell therapies based on the use …
Mesenchymal stem/stromal cells (MSCs): role as guardians of inflammation
DJ Prockop, JY Oh - Molecular therapy, 2012 - cell.com
Recent observations have demonstrated that one of the functions of mesenchymal
stem/stromal cells (MSCs) is to serve as guardians against excessive inflammatory …
stem/stromal cells (MSCs) is to serve as guardians against excessive inflammatory …
[HTML][HTML] Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease
The broad repertoire of secreted trophic and immunomodulatory cytokines produced by
mesenchymal stem cells (MSCs), generally referred to as the MSC secretome, has …
mesenchymal stem cells (MSCs), generally referred to as the MSC secretome, has …
Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident …
Human mesenchymal stem/progenitor cells (hMSCs) repair tissues and modulate immune
systems but the mechanisms are not fully understood. We demonstrated that hMSCs are …
systems but the mechanisms are not fully understood. We demonstrated that hMSCs are …
[HTML][HTML] Mesenchymal stem cell-derived exosomes reduce A1 astrocytes via downregulation of phosphorylated NFκB P65 subunit in spinal cord injury
L Wang, S Pei, L Han, B Guo, Y Li, R Duan… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Neurotoxic A1 astrocytes are induced by inflammation after spinal cord
injury (SCI), and the inflammation-related Nuclear Factor Kappa B (NFκB) pathway may be …
injury (SCI), and the inflammation-related Nuclear Factor Kappa B (NFκB) pathway may be …
[HTML][HTML] The stem cell secretome and its role in brain repair
Compelling evidence exists that non-haematopoietic stem cells, including mesenchymal
(MSCs) and neural/progenitor stem cells (NPCs), exert a substantial beneficial and …
(MSCs) and neural/progenitor stem cells (NPCs), exert a substantial beneficial and …
Stem cells as drug delivery methods: application of stem cell secretome for regeneration
C Tran, MS Damaser - Advanced drug delivery reviews, 2015 - Elsevier
Mesenchymal stem cells (MSCs) are a unique cell population defined by their ability to
indefinitely self-renew, differentiate into multiple cell lineages, and form clonal cell …
indefinitely self-renew, differentiate into multiple cell lineages, and form clonal cell …
Sepsis induces long-term metabolic and mitochondrial muscle stem cell dysfunction amenable by mesenchymal stem cell therapy
Sepsis, or systemic inflammatory response syndrome, is the major cause of critical illness
resulting in admission to intensive care units. Sepsis is caused by severe infection and is …
resulting in admission to intensive care units. Sepsis is caused by severe infection and is …