ECCO guidelines on therapeutics in Crohn's disease: surgical treatment

M Adamina, S Minozzi, J Warusavitarne… - Journal of Crohn's …, 2024 - academic.oup.com
This article is the second in a series of two publications on the European Crohn's and Colitis
Organisation [ECCO] evidence-based consensus on the management of Crohn's disease …

Management of perianal fistulizing Crohn's disease

A Singh, V Midha, GS Kochhar, B Shen… - Inflammatory Bowel …, 2024 - academic.oup.com
Perianal fistulizing Crohn's disease (CD) represents a severe phenotype of CD that is
associated with significant morbidity and reduction in quality of life. Perianal fistulizing CD is …

Where are we and where to next?—The future of perianal Crohn's disease management

S Anandabaskaran, L Hanna, N Iqbal… - Journal of Clinical …, 2023 - mdpi.com
Perianal fistulizing Crohn's Disease (pCD) affects about 25% of patients with Crohn's
Disease (CD). It remains a difficult entity to manage with a therapeutic ceiling of treatment …

Real-world experience with subcutaneous infliximab: broadening treatment strategies for inflammatory bowel disease

PJ Smith, M Fumery, RW Leong, K Novak… - Expert Review of …, 2023 - Taylor & Francis
Introduction The first subcutaneous (SC) formulation of infliximab (IFX), CT‑P13 SC, has
been approved in Europe and Australia, including for the treatment of inflammatory bowel …

Association of neutrophil extracellular traps with fistula healing in patients with complex perianal fistulizing Crohn's disease

D Cao, K Qian, Y Zhao, J Hong, H Chen… - Journal of Crohn's …, 2023 - academic.oup.com
Abstract Background and Aims Perianal fistulizing Crohn's disease [pfCD] is a disabling
phenotype of Crohn's disease [CD] with suboptimal outcomes. We assessed neutrophil …

Therapeutic drug monitoring in perianal fistulizing Crohn's disease

M Zulqarnain, P Deepak, AJ Yarur - Journal of Clinical Medicine, 2022 - mdpi.com
Perianal fistulas are a common complication of Crohn's disease (CD) that has, historically,
been challenging to manage. Despite the strong available evidence that anti-tumor necrosis …

Precision medicine in inflammatory bowel disease

Z Zeng, M Jiang, X Li, J Yuan… - Precision Clinical …, 2023 - academic.oup.com
Inflammatory bowel disease (IBD) is an incurable disease characterized by remission-
relapse cycles throughout its course. Both Crohn's disease (CD) and ulcerative colitis (UC) …

Therapeutic drug monitoring of biologics in Crohn's disease

LB Grossberg, AS Cheifetz… - Gastroenterology …, 2022 - gastro.theclinics.com
Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) that is characterized by
transmural inflammation that can affect any part of the gastrointestinal tract, leading to …

Perianal fistulizing Crohn's disease: Current perspectives on diagnosis, monitoring and management with a focus on emerging therapies

J Devi, DH Ballard, T Aswani-Omprakash… - Indian Journal of …, 2024 - Springer
Abstract Crohn's disease (CD), a chronic inflammatory bowel disorder, manifests in various
phenotypes, with fistulizing perianal CD (CD-PAF) being one of its most severe phenotypes …

Superior Efficacy of Infliximab Versus Adalimumab for First-Line Treatment of Crohn's Perianal Fistulae

L Maas, R Gao, V Cusumano, E Spartz… - Digestive diseases and …, 2023 - Springer
Background Crohn's disease perianal fistulae (CD-PAF) occur in 25% of patients and are
notoriously challenging to manage. Tumor necrosis factor inhibitors are first line agents …