The kinetoplastid protozoan parasites belonging to the genus Leishmania are the causative
agents of different clinical forms of leishmaniasis, a vector-borne infectious disease with …

In the Leishmania lifecycle, the motile promastigote form is transmitted from the sand fly
vector to a mammalian host during a blood meal. Inside vertebrate host macrophages, the …

Candida albicans is an opportunistic fungus that is part of the normal microflora commonly
found in the human digestive tract and the normal mucosa or skin of healthy individuals …

Exosomes are extracellular microvesicles of endosomal origin (multivesicular bodies, MVBs)
constitutively released by eukaryotic cells by fusion of MVBs to the plasma membrane. The …

Visceral leishmaniasis (VL) is a neglected disease considered a serious public health
problem, especially in endemic countries. Several studies have discovered monoxenous …

Leishmania amazonensis and Leishmania braziliensis are the main causative agents of
American Tegumentary Leishmaniasis (ATL) in Brazil. As intracellular parasites, the …

Most of the signaling pathways are regulated by reversible phosphorylation-
dephosphorylation which involves enzymes-kinases and phosphatases. Current knowledge …

Adjuvants represent a promising strategy to improve vaccine effectiveness against infectious
diseases such as leishmaniasis. Vaccination with the invariant natural killer T cell ligand α …

Drug resistance is a complex phenomenon during leishmaniasis chemotherapy. In this
study, the genes and pathways involved in miltefosine (MIL)-resistant Leishmania were …

Abstract Introduction: Casiopeina III-ia (CasIII-ia) is a mixed chelate copper (II) compound
capable of interacting with free radicals generated in the respiratory chain through redox …