RNA editing in the forefront of epitranscriptomics and human health

T Christofi, A Zaravinos - Journal of translational medicine, 2019 - Springer
Post-transcriptional modifications have been recently expanded with the addition of RNA
editing, which is predominantly mediated by adenosine and cytidine deaminases acting on …

Proteogenomics from a bioinformatics angle: A growing field

G Menschaert, D Fenyö - Mass spectrometry reviews, 2017 - Wiley Online Library
Proteogenomics is a research area that combines areas as proteomics and genomics in a
multi‐omics setup using both mass spectrometry and high‐throughput sequencing …

DARNED: a DAtabase of RNa EDiting in humans

A Kiran, PV Baranov - Bioinformatics, 2010 - academic.oup.com
Motivation: RNA editing is a phenomenon, which is responsible for the alteration of
particular nucleotides in RNA sequences relative to their genomic templates. Recently, a …

LNCediting: a database for functional effects of RNA editing in lncRNAs

J Gong, C Liu, W Liu, Y **ang, L Diao… - Nucleic acids …, 2017 - academic.oup.com
RNA editing is a widespread post-transcriptional mechanism that can make a single base
change on specific nucleotide sequence in an RNA transcript. RNA editing events can result …

Plant editosome database: a curated database of RNA editosome in plants

M Li, L **a, Y Zhang, G Niu, M Li, P Wang… - Nucleic Acids …, 2019 - academic.oup.com
RNA editing plays an important role in plant development and growth, enlisting a number of
editing factors in the editing process and accordingly revealing the diversity of plant …

RNA editing in plants: A comprehensive survey of bioinformatics tools and databases

CL Giudice, I Hernández, LR Ceci, G Pesole… - Plant Physiology and …, 2019 - Elsevier
RNA editing is a widespread epitranscriptomic mechanism by which primary RNAs are
specifically modified through insertions/deletions or nucleotide substitutions. In plants, RNA …

REDIdb 3.0: a comprehensive collection of RNA editing events in plant organellar genomes

C Lo Giudice, G Pesole, E Picardi - Frontiers in Plant Science, 2018 - frontiersin.org
RNA editing is an important epigenetic mechanism by which genome-encoded transcripts
are modified by substitutions, insertions and/or deletions. It was first discovered in …

Editome Disease Knowledgebase (EDK): a curated knowledgebase of editome-disease associations in human

G Niu, D Zou, M Li, Y Zhang, J Sang, L **a… - Nucleic Acids …, 2019 - academic.oup.com
RNA editing, as an essential co-/post-transcriptional RNA modification type, plays critical
roles in many biological processes and involves with a variety of human diseases. Although …

Alternative applications for distinct RNA sequencing strategies

L Han, KC Vickers, DC Samuels… - Briefings in …, 2015 - academic.oup.com
Recent advances in RNA library preparation methods, platform accessibility and cost
efficiency have allowed high-throughput RNA sequencing (RNAseq) to replace conventional …

Correlation between amino acid residues converted by RNA editing and functional residues in protein three-dimensional structures in plant organelles

K Yura, M Go - BMC Plant Biology, 2008 - Springer
Background In plant organelles, specific messenger RNAs (mRNAs) are subjected to
conversion editing, a process that often converts the first or second nucleotide of a codon …