[HTML][HTML] Signatures of HIV-1 subtype B and C Tat proteins and their effects in the neuropathogenesis of HIV-associated neurocognitive impairments

ME Williams, SS Zulu, DJ Stein, JA Joska… - Neurobiology of …, 2020 - Elsevier
HIV-associated neurocognitive impairments (HANI) are a spectrum of neurological disorders
due to the effects of HIV-1 on the central nervous system (CNS). The HIV-1 subtypes; HIV-1 …

A comparison of five brief screening tools for HIV-associated neurocognitive disorders in the USA and South Africa

JA Joska, J Witten, KG Thomas, C Robertson… - AIDS and Behavior, 2016 - Springer
Screening for HIV-associated neurocognitive disorders (HAND) is important to improve
clinical outcomes. We compared the diagnostic sensitivity and specificity of the mini-mental …

Cerebral injury in perinatally HIV-infected children compared to matched healthy controls

S Cohen, MWA Caan, HJ Mutsaerts, HJ Scherpbier… - Neurology, 2016 - AAN Enterprises
Objective: The current study aims to evaluate the neurologic state of perinatally HIV-infected
children on combination antiretroviral therapy and to attain a better insight into the …

Effect of human immunodeficiency virus on the brain: A review

K Cilliers, CJF Muller - The Anatomical Record, 2021 - Wiley Online Library
Thirty million people are infected with human immunodeficiency virus (HIV) worldwide, and
HIV‐associated neurocognitive disorder (HAND) is one of the most common comorbidities of …

Topographies of cortical and subcortical volume loss in HIV and aging in the cART era

A Guha, MR Brier, M Ortega… - JAIDS Journal of …, 2016 - journals.lww.com
Objectives: Studies of HIV-associated brain atrophy often focus on a priori brain regions of
interest, which can introduce bias. A data-driven, minimally biased approach was used to …

Effects of HIV and childhood trauma on brain morphometry and neurocognitive function

G Spies, F Ahmed-Leitao, C Fennema-Notestine… - Journal of …, 2016 - Springer
A wide spectrum of neurocognitive deficits characterises HIV infection in adults. HIV infection
is additionally associated with morphological brain abnormalities affecting neural substrates …

Association of immunosuppression and viral load with subcortical brain volume in an international sample of people living with HIV

TM Nir, JP Fouche, J Ananworanich… - JAMA network …, 2021 - jamanetwork.com
Importance Despite more widely accessible combination antiretroviral therapy (cART), HIV-1
infection remains a global public health challenge. Even in treated patients with chronic HIV …

Increased Peripheral Inflammation Is Associated With Structural Brain Changes and Reduced Blood Flow in People With Virologically Controlled HIV

TH Burdo, JA Robinson, S Cooley… - The Journal of …, 2023 - academic.oup.com
Background While antiretroviral therapy (ART) has improved outcomes for people with HIV
(PWH), brain dysfunction is still evident. Immune activation and inflammation remain …

[HTML][HTML] Anterior and posterior thalamic volumes differentially correlate with memory, attention, and motor processes in HIV infection and alcohol use disorder …

R Fama, SA Sassoon, EM Müller-Oehring… - Brain Research …, 2024 - Elsevier
The thalamus, with its reciprocal connections to and from cortical, subcortical, and cerebellar
regions, is a central active participant in multiple functional brain networks. Structural MRI …

The effect of central nervous system penetration effectiveness of highly active antiretroviral therapy on neuropsychological performance and neuroimaging in HIV …

LM Baker, RH Paul, JM Heaps-Woodruff… - Journal of Neuroimmune …, 2015 - Springer
The incidence of HIV-associated dementia has been greatly reduced in the era of highly
active antiretroviral therapy (HAART); however milder forms of cognitive impairment persist …