Current cancer immunotherapies are primarily predicated on αβ T cells, with a stringent
dependence on MHC-mediated presentation of tumour-enriched peptides or unique …

Immunotherapies have revolutionized the treatment paradigms of various types of cancers.
However, most of these immunomodulatory strategies focus on harnessing adaptive …

γδ T cells have recently gained considerable attention as an attractive tool for cancer
adoptive immunotherapy due to their potent anti-tumor activity and unique role in …

T cell-based immunotherapies have revolutionized treatment paradigms in various cancers,
however, limited response rates secondary to lack of significant T-cell infiltration in the tumor …

Bispecific T cell engagers (bsTCEs) hold great promise for cancer treatment but face
challenges due to the induction of cytokine release syndrome (CRS), on-target off-tumor …

The tumor immune microenvironment contributes to tumor initiation, progression, and
response to therapy. Among the immune cell subsets that play a role in the tumor …

Allogeneic hematopoetic stem cell transplantation (HCT) offers an option for patients with
hematologic malignancies, in whom conventional standard therapies failed or are not …

Background Adoptive immunotherapy is gaining momentum to fight malignancies, whereby
γδ T cells have received recent attention as an alternative cell source as to natural killer cells …

There is increasing clinical evidence indicating that the immune system may either promote
or inhibit tumor progression. Several studies have demonstrated that tumors undergoing …

The tumor immune microenvironment contributes to tumor initiation, progression and
response to therapy. Among the immune cell subsets that play a role in the tumor …