Tunable metal–organic frameworks assist in catalyzing DNAzymes with amplification platforms for biomedical applications

X Zhu, J Xu, G Ling, P Zhang - Chemical Society Reviews, 2023 - pubs.rsc.org
Various binding modes of tunable metal organic frameworks (MOFs) and functional
DNAzymes (Dzs) synergistically catalyze the emergence of abundant functional …

Dynamic boronate esters cross-linked guanosine hydrogels: A promising biomaterial for emergent applications

T Ghosh, AK Das - Coordination Chemistry Reviews, 2023 - Elsevier
Over the last few decades, dynamic covalent chemistry has been successfully employed to
develop smart functional self-assembled soft materials with ubiquitous properties. Boronic …

Engineering DNA G-quadruplex assembly for label-free detection of Ochratoxin A in colorimetric and fluorescent dual modes

K He, L Sun, L Wang, W Li, G Hu, X Ji, Y Zhang… - Journal of Hazardous …, 2022 - Elsevier
Colorimetric and fluorescent methods for Ochratoxin A (OTA) detection are convenient and
well received. However, the pigments and autofluorescence originated from food matrices …

DNA assembly‐based stimuli‐responsive systems

S Lu, J Shen, C Fan, Q Li, X Yang - Advanced Science, 2021 - Wiley Online Library
Stimuli‐responsive designs with exogenous stimuli enable remote and reversible control of
DNA nanostructures, which break many limitations of static nanostructures and inspired …

Hemin-bridged MOF interface with double amplification of G-quadruplex payload and DNAzyme catalysis: ultrasensitive lasting chemiluminescence microRNA …

L Mi, Y Sun, L Shi, T Li - ACS applied materials & interfaces, 2020 - ACS Publications
Here, we report a double-amplified sensing platform for ultrasensitive chemiluminescence
(CL) miRNA detection in real patients' blood in which a hemin-bridged metal–organic …

Bioinspired supramolecular catalysts from designed self-assembly of DNA or peptides

S Liu, P Du, H Sun, HY Yu, ZG Wang - ACS Catalysis, 2020 - ACS Publications
Enzymes play vital roles in cellular functions by catalyzing biochemical reactions in high
activity and selectivity, which is largely attributed to the cooperation between the exquisitely …

Functional Nucleic Acid Enzymes: Nucleic Acid-Based Catalytic Factories

M Yang, Y **e, L Zhu, X Li, W Xu - Acs Catalysis, 2024 - ACS Publications
Biocatalysis plays a vital role in the operations of all living organisms, which is usually
thought to be mediated by protein enzymes. However, the pioneering discovery of self …

Highly sensitive biosensing applications of a magnetically immobilizable covalent G-quadruplex-hemin DNAzyme catalytic system

Y Chen, D Qiu, X Zhang, Y Liu, M Cheng, J Lei… - Analytical …, 2022 - ACS Publications
G-quadruplex/hemin (G4/hemin) DNAzymes are biosensing systems, but their application
remains limited by an overall low activity and a rather high level of unwarranted background …

Engineering of nucleic acids and synthetic cofactors as holo sensors for probing signaling molecules in the cellular membrane microenvironment

G Feng, X Luo, X Lu, S **e, L Deng, W Kang… - Angewandte …, 2019 - Wiley Online Library
The comprehensive understanding of the mechanisms underlying the interaction of cells
with their membrane microenvironment is of great value for fundamental biological research; …

Biosensors made of synthetic functional nucleic acids toward better human health

EM McConnell, I Cozma, D Morrison, Y Li - Analytical Chemistry, 2019 - ACS Publications
The invention of the in vitro selection technique, or SELEX (Systematic Evolution of Ligands
by EXponential enrichment), in the early 1990s, identified single-stranded (ss) nucleic acid …