Tunable metal–organic frameworks assist in catalyzing DNAzymes with amplification platforms for biomedical applications
X Zhu, J Xu, G Ling, P Zhang - Chemical Society Reviews, 2023 - pubs.rsc.org
Various binding modes of tunable metal organic frameworks (MOFs) and functional
DNAzymes (Dzs) synergistically catalyze the emergence of abundant functional …
DNAzymes (Dzs) synergistically catalyze the emergence of abundant functional …
Dynamic boronate esters cross-linked guanosine hydrogels: A promising biomaterial for emergent applications
Over the last few decades, dynamic covalent chemistry has been successfully employed to
develop smart functional self-assembled soft materials with ubiquitous properties. Boronic …
develop smart functional self-assembled soft materials with ubiquitous properties. Boronic …
Engineering DNA G-quadruplex assembly for label-free detection of Ochratoxin A in colorimetric and fluorescent dual modes
Colorimetric and fluorescent methods for Ochratoxin A (OTA) detection are convenient and
well received. However, the pigments and autofluorescence originated from food matrices …
well received. However, the pigments and autofluorescence originated from food matrices …
DNA assembly‐based stimuli‐responsive systems
Stimuli‐responsive designs with exogenous stimuli enable remote and reversible control of
DNA nanostructures, which break many limitations of static nanostructures and inspired …
DNA nanostructures, which break many limitations of static nanostructures and inspired …
Hemin-bridged MOF interface with double amplification of G-quadruplex payload and DNAzyme catalysis: ultrasensitive lasting chemiluminescence microRNA …
Here, we report a double-amplified sensing platform for ultrasensitive chemiluminescence
(CL) miRNA detection in real patients' blood in which a hemin-bridged metal–organic …
(CL) miRNA detection in real patients' blood in which a hemin-bridged metal–organic …
Bioinspired supramolecular catalysts from designed self-assembly of DNA or peptides
Enzymes play vital roles in cellular functions by catalyzing biochemical reactions in high
activity and selectivity, which is largely attributed to the cooperation between the exquisitely …
activity and selectivity, which is largely attributed to the cooperation between the exquisitely …
Functional Nucleic Acid Enzymes: Nucleic Acid-Based Catalytic Factories
M Yang, Y **e, L Zhu, X Li, W Xu - Acs Catalysis, 2024 - ACS Publications
Biocatalysis plays a vital role in the operations of all living organisms, which is usually
thought to be mediated by protein enzymes. However, the pioneering discovery of self …
thought to be mediated by protein enzymes. However, the pioneering discovery of self …
Highly sensitive biosensing applications of a magnetically immobilizable covalent G-quadruplex-hemin DNAzyme catalytic system
Y Chen, D Qiu, X Zhang, Y Liu, M Cheng, J Lei… - Analytical …, 2022 - ACS Publications
G-quadruplex/hemin (G4/hemin) DNAzymes are biosensing systems, but their application
remains limited by an overall low activity and a rather high level of unwarranted background …
remains limited by an overall low activity and a rather high level of unwarranted background …
Engineering of nucleic acids and synthetic cofactors as holo sensors for probing signaling molecules in the cellular membrane microenvironment
G Feng, X Luo, X Lu, S **e, L Deng, W Kang… - Angewandte …, 2019 - Wiley Online Library
The comprehensive understanding of the mechanisms underlying the interaction of cells
with their membrane microenvironment is of great value for fundamental biological research; …
with their membrane microenvironment is of great value for fundamental biological research; …
Biosensors made of synthetic functional nucleic acids toward better human health
The invention of the in vitro selection technique, or SELEX (Systematic Evolution of Ligands
by EXponential enrichment), in the early 1990s, identified single-stranded (ss) nucleic acid …
by EXponential enrichment), in the early 1990s, identified single-stranded (ss) nucleic acid …