Molecular probes for autofluorescence-free optical imaging

Y Jiang, K Pu - Chemical reviews, 2021 - ACS Publications
Optical imaging is an indispensable tool in clinical diagnostics and fundamental biomedical
research. Autofluorescence-free optical imaging, which eliminates real-time optical …

Phosphorescent iridium (III) complexes as lifetime-based biological sensors for photoluminescence lifetime imaging microscopy

J Zhou, J Li, KY Zhang, S Liu, Q Zhao - Coordination Chemistry Reviews, 2022 - Elsevier
Luminescent iridium (III) complexes exhibit high phosphorescence quantum yields and
photostability, good cell membrane permeability, rich and sensitive photophysical …

Fluorescence lifetime imaging with a megapixel SPAD camera and neural network lifetime estimation

V Zickus, ML Wu, K Morimoto, V Kapitany, A Fatima… - Scientific Reports, 2020 - nature.com
Fluorescence lifetime imaging microscopy (FLIM) is a key technology that provides direct
insight into cell metabolism, cell dynamics and protein activity. However, determining the …

Entangled photon correlations allow a continuous-wave laser diode to measure single-photon, time-resolved fluorescence

N Harper, BP Hickam, M He… - The Journal of Physical …, 2023 - ACS Publications
Fluorescence lifetime experiments are a standard approach for measuring excited-state
dynamics and local environmental effects. Here, we show that entangled photon pairs …

[Retracted] Fluorescent Carbon Dot‐Supported Imaging‐Based Biomedicine: A Comprehensive Review

LMT Phan, S Cho - Bioinorganic chemistry and applications, 2022 - Wiley Online Library
Carbon dots (CDs) provide distinctive advantages of strong fluorescence, good
photostability, high water solubility, and outstanding biocompatibility, and thus are widely …

Cubosome nanoparticles for enhanced delivery of mitochondria anticancer drug elesclomol and therapeutic monitoring via sub-cellular NAD (P) H multi-photon …

AR Faria, OF Silvestre, C Maibohm, RMR Adão… - Nano Research, 2019 - Springer
Elesclomol (ELC) is an anticancer drug inducing mitochondria cytotoxicity through reactive
oxygen species. Here, for the first time, we encapsulate the poorly water soluble ELC in …

Intravital microscopy for real-time monitoring of drug delivery and nanobiological processes

J Momoh, D Kapsokalyvas, M Vogt, S Hak… - Advanced Drug Delivery …, 2022 - Elsevier
Intravital microscopy (IVM) expands our understanding of cellular and molecular processes,
with applications ranging from fundamental biology to (patho) physiology and immunology …

Single-photon peak event detection (SPEED): a computational method for fast photon counting in fluorescence lifetime imaging microscopy

JE Sorrells, RR Iyer, L Yang, EJ Chaney… - Optics …, 2021 - opg.optica.org
Fluorescence lifetime imaging microscopy (FLIM) characterizes samples by examining the
temporal properties of fluorescence emission, providing useful contrast within samples …

Single-shot time-folded fluorescence lifetime imaging

V Kapitany, V Zickus, A Fatima… - Proceedings of the …, 2023 - National Acad Sciences
Fluorescence lifetime imaging is an important tool in bioimaging that allows one to detect
subtle changes in cell dynamics and their environment. Most time-domain approaches …

Alzheimer's Disease: Status of Low‐Dimensional Nanotherapeutic Materials

D Huang, W Liao, J Li, T Chen, X Wang… - Advanced Functional …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease that
constitutes the third most common cause of death among elderly individuals. AD patients …