MicroRNAs are small double-stranded RNAs, which negatively regulate gene expression
and have been shown to have key roles in both chondrocyte development and cartilage …

MicroRNAs (miRNAs) repress cellular protein levels to provide a sophisticated parameter of
gene regulation that coordinates a broad spectrum of biological processes. Bone …

By comparing the expression profiles of microRNAs (miRNAs) in different hepatocellular
carcinoma (HCC) subtypes, we identified miR‐140‐5p as an HCC‐related miRNA. We …

Background—Pulmonary hypertension (PH) is driven by diverse pathogenic etiologies.
Owing to their pleiotropic actions, microRNA molecules are potential candidates for …

Chondrogenic differentiation of mesenchymal stem cells (MSCs) is accurately regulated by
essential transcription factors and signaling cascades. However, the precise mechanisms …

Objective To use an in vitro model of chondrogenesis to identify microRNAs (miRNAs) with a
functional role in cartilage homeostasis. Methods The expression of miRNAs was measured …

The activin/transforming growth factor-β (TGF-β) pathway plays an important role in
tumorigenesis either by its tumor suppressor or tumor promoting effect. Loss of members of …

Osteoarthritis (OA) is a complex multifactorial disease with a strong genetic component.
Several studies have suggested or identified epigenetic events that may play a role in OA …

MicroRNAs have been shown to function in cartilage development and homeostasis, as well
as in progression of osteoarthritis. The objective of the current study was to identify …

Osteoarthritis (OA) is a multifactorial disease subject to the effects of many genes and
environmental factors. Alterations in the normal pattern of chondrocyte gene control in …