[HTML][HTML] Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape

NI Mazur, J Terstappen, R Baral, A Bardají… - The Lancet Infectious …, 2023 - thelancet.com
Respiratory syncytial virus is the second most common cause of infant mortality and a major
cause of morbidity and mortality in older adults (aged> 60 years). Efforts to develop a …

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates

NI Mazur, D Higgins, MC Nunes, JA Melero… - The Lancet Infectious …, 2018 - thelancet.com
The global burden of disease caused by respiratory syncytial virus (RSV) is increasingly
recognised, not only in infants, but also in older adults (aged≥ 65 years). Advances in …

Prefusion F protein–based respiratory syncytial virus immunization in pregnancy

EAF Simões, KJ Center, ATN Tita… - … England Journal of …, 2022 - Mass Medical Soc
Background Respiratory syncytial virus (RSV), a major cause of illness and death in infants
worldwide, could be prevented by vaccination during pregnancy. The efficacy …

Rational design of a highly immunogenic prefusion-stabilized F glycoprotein antigen for a respiratory syncytial virus vaccine

Y Che, AV Gribenko, X Song, LD Handke… - Science Translational …, 2023 - science.org
Respiratory syncytial virus (RSV) is the leading, global cause of serious respiratory disease
in infants and is an important cause of respiratory illness in older adults. No RSV vaccine is …

Palivizumab for preventing severe respiratory syncytial virus (RSV) infection in children

L Garegnani, L Styrmisdóttir… - Cochrane Database …, 2021 - cochranelibrary.com
Background Respiratory viruses are the leading cause of lower respiratory tract infection
(LRTI) and hospitalisation in infants and young children. Respiratory syncytial virus (RSV) is …

Integrated omics endoty** of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma

Y Raita, M Pérez-Losada, RJ Freishtat… - Nature …, 2021 - nature.com
Respiratory syncytial virus (RSV) bronchiolitis is not only the leading cause of hospitalization
in US infants, but also a major risk factor for asthma development. While emerging evidence …

[HTML][HTML] Immunopathology of RSV: an updated review

HC Bergeron, RA Tripp - Viruses, 2021 - mdpi.com
RSV is a leading cause of respiratory tract disease in infants and the elderly. RSV has
limited therapeutic interventions and no FDA-approved vaccine. Gaps in our understanding …

Respiratory syncytial virus (RSV): a scourge from infancy to old age

JA Coultas, R Smyth, PJ Openshaw - Thorax, 2019 - thorax.bmj.com
Respiratory syncytial virus (RSV) is the most common single cause of respiratory
hospitalisation of infants and is the second largest cause of lower respiratory infection …

Receptors for respiratory syncytial virus infection and host factors regulating the life cycle of respiratory syncytial virus

Z Feng, L Xu, Z **e - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract infections and
responsible for a large proportion of mortality in children and the elderly. There are no …

The repertoire of maternal anti-viral antibodies in human newborns

C Pou, D Nkulikiyimfura, E Henckel, A Olin… - Nature medicine, 2019 - nature.com
All circulating immunoglobulin G (IgG) antibodies in human newborns are of maternal origin
and transferred across the placenta to provide passive immunity until newborn IgG …