The development of nociceptive circuits
M Fitzgerald - Nature Reviews Neuroscience, 2005 - nature.com
The study of pain development has come into its own. Rea** the rewards of years of
developmental and molecular biology, it has now become possible to translate fundamental …
developmental and molecular biology, it has now become possible to translate fundamental …
Impact of repeated procedural pain-related stress in infants born very preterm
The majority of infants born very preterm (24–32 wk gestational age) now survive; however,
long-term neurodevelopmental and behavioral problems remain a concern. As part of their …
long-term neurodevelopmental and behavioral problems remain a concern. As part of their …
Prevention and management of procedural pain in the neonate: an update
E Keels, N Sethna, KL Watterberg, JJ Cummings… - …, 2016 - publications.aap.org
Background Neonates are frequently subjected to painful procedures, with the most
immature infants receiving the highest number of painful events. 3,–5 Despite …
immature infants receiving the highest number of painful events. 3,–5 Despite …
Infant pain management: a developmental neurobiological approach
Infant pain is a clinical reality. Effective pain management in infants requires a specialist
approach—analgesic protocols that have been designed for older children cannot simply be …
approach—analgesic protocols that have been designed for older children cannot simply be …
Book Review: The neurobiology of pain: Developmental aspects
Invasive procedures that would be painful in children and adults are frequently performed on
infants admitted to the neonatal intensive care unit. This article discusses sensory responses …
infants admitted to the neonatal intensive care unit. This article discusses sensory responses …
Circuits for gras**: spinal dI3 interneurons mediate cutaneous control of motor behavior
Accurate motor performance depends on the integration in spinal microcircuits of sensory
feedback information. Hand grasp is a skilled motor behavior known to require cutaneous …
feedback information. Hand grasp is a skilled motor behavior known to require cutaneous …
The postnatal development of spinal sensory processing
The mechanisms by which infants and children process pain should be viewed within the
context of a develo** sensory nervous system. The study of the neurophysiological …
context of a develo** sensory nervous system. The study of the neurophysiological …
Hindpaw incision in early life increases the hyperalgesic response to repeat surgical injury: critical period and dependence on initial afferent activity
Pain in early life can enhance the response to subsequent injury, but effects are influenced
by both the nature and timing of neonatal injury. Using plantar hindpaw incision, we …
by both the nature and timing of neonatal injury. Using plantar hindpaw incision, we …
The postnatal reorganization of primary afferent input and dorsal horn cell receptive fields in the rat spinal cord is an activity‐dependent process
The dorsal horn of the spinal cord in the newborn rat is characterized by large cutaneous
mechanoreceptive fields, a predominance of A‐fibre synaptic inputs and diffuse primary …
mechanoreceptive fields, a predominance of A‐fibre synaptic inputs and diffuse primary …
Cutaneous flexion reflex in human neonates: a quantitative study of threshold and stimulus-response characteristics after single and repeated stimuli
K Andrews, M Fitzgerald - Developmental medicine and child …, 1999 - cambridge.org
The cutaneous flexion reflex has been used to study spinal sensory processing in 68 infants
(37 female, 31 male) aged between 28 and 42 weeks postconceptional age (PCA) …
(37 female, 31 male) aged between 28 and 42 weeks postconceptional age (PCA) …