Prevention of stroke: a global perspective

JD Pandian, SL Gall, MP Kate, GS Silva, RO Akinyemi… - The Lancet, 2018 - thelancet.com
Along with the rising global burden of disability attributed to stroke, costs of stroke care are
rising, providing the impetus to direct our research focus towards effective measures of …

Medication adherence in cardiovascular medicine

ST Simon, V Kini, AE Levy, PM Ho - Bmj, 2021 - bmj.com
Cardiovascular disease is the leading cause of death globally. While pharmacological
advancements have improved the morbidity and mortality associated with cardiovascular …

[HTML][HTML] Polypill strategy in secondary cardiovascular prevention

JM Castellano, SJ Pocock, DL Bhatt… - … England Journal of …, 2022 - Mass Medical Soc
Background A polypill that includes key medications associated with improved outcomes
(aspirin, angiotensin-converting–enzyme [ACE] inhibitor, and statin) has been proposed as …

Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial

G Roshandel, M Khoshnia, H Poustchi, K Hemming… - The Lancet, 2019 - thelancet.com
Background A fixed-dose combination therapy (polypill strategy) has been proposed as an
approach to reduce the burden of cardiovascular disease, especially in low-income and …

How to optimize the adherence to a guideline-directed medical therapy in the secondary prevention of cardiovascular diseases: a clinical consensus statement from …

RFE Pedretti, D Hansen, M Ambrosetti… - European journal of …, 2023 - academic.oup.com
A key factor to successful secondary prevention of cardiovascular disease (CVD) is optimal
patient adherence to treatment. However, unsatisfactory rates of adherence to treatment for …

A polypill strategy to improve adherence: results from the FOCUS project

JM Castellano, G Sanz, JL Peñalvo, S Bansilal… - Journal of the American …, 2014 - jacc.org
Background: Adherence to evidence-based cardiovascular (CV) medications after an acute
myocardial infarction (MI) is low after the first 6 months. The use of fixed-dose combinations …

[HTML][HTML] Polypill for cardiovascular disease prevention in an underserved population

D Muñoz, P Uzoije, C Reynolds, R Miller… - … England Journal of …, 2019 - Mass Medical Soc
Background Persons with low socioeconomic status and nonwhite persons in the United
States have high rates of cardiovascular disease. The use of combination pills (also called …

Interventions for improving medication‐taking ability and adherence in older adults prescribed multiple medications

AJ Cross, RA Elliott, K Petrie… - Cochrane Database …, 2020 - cochranelibrary.com
Background Older people taking multiple medications represent a large and growing
proportion of the population. Managing multiple medications can be challenging, and this is …

Effect of fixed dose combination treatment on adherence and risk factor control among patients at high risk of cardiovascular disease: randomised controlled trial in …

V Selak, CR Elley, C Bullen, S Crengle, A Wadham… - Bmj, 2014 - bmj.com
Objective To evaluate whether provision of fixed dose combination treatment improves
adherence and risk factor control compared with usual care of patients at high risk of …

Interventions to improve adherence to lipid‐lowering medication

ML van Driel, MD Morledge, R Ulep… - Cochrane Database …, 2016 - cochranelibrary.com
Background Lipid‐lowering drugs are widely underused, despite strong evidence indicating
they improve cardiovascular end points. Poor patient adherence to a medication regimen …