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Recurrent topics in mass spectrometry-based metabolomics and lipidomics—standardization, coverage, and throughput
We have come a long way in the last years of develo** analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …
Integrative omics approaches for biosynthetic pathway discovery in plants
Covering: up to 2022 With the emergence of large amounts of omics data, computational
approaches for the identification of plant natural product biosynthetic pathways and their …
approaches for the identification of plant natural product biosynthetic pathways and their …
Feature-based molecular networking in the GNPS analysis environment
Molecular networking has become a key method to visualize and annotate the chemical
space in non-targeted mass spectrometry data. We present feature-based molecular …
space in non-targeted mass spectrometry data. We present feature-based molecular …
NPClassifier: a deep neural network-based structural classification tool for natural products
Computational approaches such as genome and metabolome mining are becoming
essential to natural products (NPs) research. Consequently, a need exists for an automated …
essential to natural products (NPs) research. Consequently, a need exists for an automated …
Database-independent molecular formula annotation using Gibbs sampling through ZODIAC
The confident high-throughput identification of small molecules is one of the most
challenging tasks in mass spectrometry-based metabolomics. Annotating the molecular …
challenging tasks in mass spectrometry-based metabolomics. Annotating the molecular …
Deep learning meets metabolomics: a methodological perspective
Deep learning (DL), an emerging area of investigation in the fields of machine learning and
artificial intelligence, has markedly advanced over the past years. DL techniques are being …
artificial intelligence, has markedly advanced over the past years. DL techniques are being …
Anaerobic gut fungi are an untapped reservoir of natural products
Anaerobic fungi (class Neocallimastigomycetes) thrive as low-abundance members of the
herbivore digestive tract. The genomes of anaerobic gut fungi are poorly characterized and …
herbivore digestive tract. The genomes of anaerobic gut fungi are poorly characterized and …
A polysaccharide utilization locus from the gut bacterium Dysgonomonas mossii encodes functionally distinct carbohydrate esterases
The gut microbiota plays a central role in human health by enzymatically degrading dietary
fiber and concomitantly excreting short chain fatty acids that are associated with manifold …
fiber and concomitantly excreting short chain fatty acids that are associated with manifold …
[HTML][HTML] Untargeted metabolomics revealed essential biochemical rearrangements towards combined heat and drought stress acclimatization in Pinus pinaster
Trees usually face simultaneous stresses and have evolved to deal with them naturally.
However, as a consequence of climate change, heat waves and drought stress have …
However, as a consequence of climate change, heat waves and drought stress have …
The LOTUS initiative for open natural products research: knowledge management through Wikidata
As contemporary bioinformatic and chemoinformatic capabilities are resha** natural
products research, major benefits could result from an open database of referenced …
products research, major benefits could result from an open database of referenced …