The term “undruggable” refers to proteins or other biological targets that have been
historically challenging to target with conventional drugs or therapeutic strategies because …

In recent years, visible light-induced reactions of diazo compounds have attracted
increasing attention in organic synthesis, leading to improvement of existing reactions, as …

Phase-separated condensates are membrane-less intracellular structures comprising
dynamic protein interactions that organize essential biological processes. Understanding …

State-of-the-art methods in photoproximity labeling center on the targeted generation and
capture of short-lived reactive intermediates to provide a snapshot of local protein …

With the advent of photoredox catalysis, new synthetic paradigms have been established
with many novel transformations being achieved. Nevertheless, modern photoredox …

Cancer remains one of the most difficult human diseases to overcome because of its
complexity and diversity. Signal transducers and transcriptional activators 3 (STAT3) protein …

The proteome, or collection of proteoforms expressed in a biological system, is dynamic and
heterogeneous. As our appreciation for the complexity of the proteome has evolved, so have …

Unlocking the reactivity of diazo compounds in red light with the use of photochemical tools -
Chemical Communications (RSC Publishing) DOI:10.1039/D3CC05174A Royal Society of …

Alismatis Rhizoma (AR), a traditional Chinese medicine for treating obesity in traditional
Chinese medicine clinic, is recognized as a promising source of lead compounds of lipase …

Despite the advent of various medical interventions for cancer treatment, the disease
continues to pose a formidable global health challenge, necessitating the development of …