The main focus of this review is the role of mammary stem cells in normal breast
development and carcinogenesis. We have developed a new in vitro culture system that …

In tissue engineering, 3D printing represents a versatile technology employing inks to
construct three-dimensional living structures, mimicking natural biological systems. This …

Transformed stem cells have been isolated from some human cancers. We report that,
unlike other brain cancers, the lethal glioblastoma multiforme contains neural precursors …

Human pluripotent stem cells (hPSCs) have been differentiated efficiently to neuronal cell
types. However, directed differentiation of hPSCs to astrocytes and astroglial subtypes …

Neural stem cells (NSCs) yield both neuronal and glial progeny, but their differentiation
potential toward multiple region-specific neuron types remains remarkably poor. In contrast …

Here we present a protocol for extraction and culture of neurons from adult rat or mouse
CNS. The method proscribes an optimized protease digestion of slices, control of osmolarity …

Neurogenesis occurs in the adult mammalian brain and may play roles in learning and
memory processes and recovery from injury, suggesting that abnormalities in neural …

Differentiation of astrocytes from human stem cells has significant potential for analysis of
their role in normal brain function and disease, but existing protocols generate only …

Regionally and functionally diverse types of astrocytes exist throughout the central nervous
system and participate in nearly every aspect of normal and abnormal neural function …

New neurons are generated throughout adulthood in two regions of the brain, the olfactory
bulb and dentate gyrus of the hippocampus, and are incorporated into the hippocampal …