Potential applications and perspectives of humanized mouse models

W Ye, Q Chen - Annual Review of Animal Biosciences, 2022 - annualreviews.org
As medical and pharmacological technology advances, new and complex modalities of
disease treatment that are more personalized and targeted are being developed. Often …

Mechanistic elucidation of human pancreatic acinar development using single-cell transcriptome analysis on a human iPSC differentiation model

A Mima, A Kimura, R Ito, Y Hatano, H Tsujimoto… - Scientific Reports, 2025 - nature.com
Few effective treatments have been developed for intractable pancreatic exocrine disorders
due to the lack of suitable disease models using human cells. Pancreatic acinar cells …

[HTML][HTML] EK-16A liposomes enhance HIV replication in ACH2 or J-Lat 10.6 cell engrafted NSG mice

P Lu, J Yang, X Yang, Z Liang, J Wang, Y Wang… - …, 2022 - ncbi.nlm.nih.gov
Background: Numbers of HIV latency reversal agents (LRAs) have been tested in clinical
trials, but with limited effect. EK-16A is an ingenol derivative that isolated from Euphorbia …