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[HTML][HTML] Pharmacokinetic aspects of retinal drug delivery
Drug delivery to the posterior eye segment is an important challenge in ophthalmology,
because many diseases affect the retina and choroid leading to impaired vision or …
because many diseases affect the retina and choroid leading to impaired vision or …
The role of anti-vascular endothelial growth factor (anti-VEGF) in the management of proliferative diabetic retinopathy
Y Zhao, RP Singh - Drugs in context, 2018 - pmc.ncbi.nlm.nih.gov
Diabetes is a major cause of visual impairment among working-age adults in the United
States. The proliferative form of diabetic retinopathy is associated with severe vision loss …
States. The proliferative form of diabetic retinopathy is associated with severe vision loss …
Ocular novel drug delivery: impacts of membranes and barriers
Background: Ocular drug delivery is an extremely challenging area due to its restrictive
barrier functionalities. Objective: Drug transport via corneal/non-corneal routes involves …
barrier functionalities. Objective: Drug transport via corneal/non-corneal routes involves …
Liposomes for intravitreal drug delivery: a state of the art
A Bochot, E Fattal - Journal of Controlled Release, 2012 - Elsevier
Intravitreal administration of drugs has raised a large interest during the last two decades
improving the treatment of infectious diseases of the posterior segment of the eye or …
improving the treatment of infectious diseases of the posterior segment of the eye or …
Intraocular nano-microscale drug delivery systems for glaucoma treatment: design strategies and recent progress
Y Shen, J Sun, X Sun - Journal of Nanobiotechnology, 2023 - Springer
Glaucoma is a leading cause of irreversible visual impairment and blindness, affecting over
76.0 million people worldwide in 2020, with a predicted increase to 111.8 million by 2040 …
76.0 million people worldwide in 2020, with a predicted increase to 111.8 million by 2040 …
Nanoparticles toxicity and their routes of exposures
Nanotechnology is a new area that presents small sized materials, structures, devices, and
systems in last few decades. We hear about many materials and systems that contain …
systems in last few decades. We hear about many materials and systems that contain …
Safety evaluation of ocular drug delivery formulations: techniques and practical considerations
BG Short - Toxicologic pathology, 2008 - journals.sagepub.com
Development of new drug candidates and novel delivery techniques for treatment of ocular
diseases has recently accelerated. Treatment of anterior-segment diseases has witnessed …
diseases has recently accelerated. Treatment of anterior-segment diseases has witnessed …
Encapsulation of dexamethasone into biodegradable polymeric nanoparticles
C Gómez-Gaete, N Tsapis, M Besnard, A Bochot… - International journal of …, 2007 - Elsevier
The present paper concerns both the optimization of dexamethasone (DXM) entrapment and
its release from biodegradable poly (d, l-lactide-co-glycolide)(PLGA) nanoparticles prepared …
its release from biodegradable poly (d, l-lactide-co-glycolide)(PLGA) nanoparticles prepared …
Drug delivery to the retina: challenges and opportunities
S Duvvuri, S Majumdar, AK Mitra - Expert opinion on biological …, 2003 - Taylor & Francis
Retinal drug delivery is a challenging area in the field of ophthalmic drug delivery. An ideal
drug delivery system for the retina and vitreous humor has not yet been found, despite …
drug delivery system for the retina and vitreous humor has not yet been found, despite …
Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration
Retinal neuroinflammation, mediated by activated microglia, plays a key role in the
pathogenesis of photoreceptor and retinal pigment epithelial cell loss in age-related macular …
pathogenesis of photoreceptor and retinal pigment epithelial cell loss in age-related macular …