Insights into the Theranostic Activity of Nonoxido VIV: Lysosome-Targeted Anticancer Metallodrugs

PD Pattanayak, A Banerjee, G Sahu, S Das… - Inorganic …, 2024 - ACS Publications
Develo** new anticancer agents can be useful, with the ability to diagnose and treat
cancer worldwide. Previously, we focused on examining the effects of nonoxidovanadium …

Hydrolytically Stable TiIV–Hydrazone-Based Metallodrugs: Protein Interaction and Anticancer Potential

G Sahu, K Sahu, SA Patra, D Mohapatra… - ACS Applied Bio …, 2023 - ACS Publications
In this work, three titanium (IV)[TiIV (L1–3) 2](1–3) complexes have been reported using
three different tridentate dibasic ONO donor hydrazone ligands, pyridine-4-carboxylic acid (3 …

Synthesis, anticancer activity, and mechanistic investigations of aryl-alkyl diorganotin arylformylhydrazone complexes

W Jiang, Q Luo, W Huang, Y Tan, Y Peng - Journal of Inorganic …, 2025 - Elsevier
Diorganotin acylhydrazone complexes with mitochondrial targeting demonstrate significant
potential as replacements for platinum-based complexes due to their potent anticancer …

RuIII–Morpholine-Derived Thiosemicarbazone-Based Metallodrugs: Lysosome-Targeted Anticancer Agents

M Mohanty, S Das, PD Pattanayak, S Lima… - ACS Applied Bio …, 2025 - ACS Publications
The idea of coordinating biologically active ligand systems to metal centers to exploit their
synergistic effects has gained momentum. Therefore, in this report, three RuIII complexes 1 …

Organotin (IV) Compounds as Catalysts for the Solvent-Free Synthesis of Naphthofurans

M Kumar, HP Nayek - Organometallics, 2024 - ACS Publications
Four distinct organotin (IV) compounds,[R2Sn (L1)][R= Ph (1) and n-Bu (2)] and [R2Sn
(L2)][R= Ph (3) and n-Bu (4)], have been synthesized from two polydentate proligands such …

Copper-assisted anticancer activity of hydroxycinnamic acid terpyridine conjugates on triple-negative breast cancer

A Roy, S Khatun, PD Dewale, AK Rengan… - Dalton …, 2024 - pubs.rsc.org
The development of active therapeutic agents to treat highly metastatic cancer while
minimizing damage to healthy cells is of utmost importance. Due to potential antioxidant …

Design, synthesis and mechanistic studies of novel arylformylhydrazone butylphenyltin complexes as potential anticancer agents

W Jiang, S Fan, Z Zhu, H Huang, Y Tan, Y Peng - Bioorganic Chemistry, 2024 - Elsevier
Many diorganotin complexes with various alkyl groups exhibit excellent in vitro anticancer
activity. However, most diorganotin is the same alkyl group, and the asymmetric alkyl R …

Syntheses and exploration of the catalytic activities of organotin (iv) compounds

M Kumar, HP Nayek - Dalton Transactions, 2024 - pubs.rsc.org
Six organotin (IV) compounds (1–6) have been synthesized by reaction of the polydentate
pro-ligands H3L and H2L, respectively, with the corresponding diorganotin chlorides. All of …

Diorganotin (IV) Complexes Containing Hydrazone Ligands as Prospective Bioactive Agents: Synthesis, Crystal Structure, Spectroscopic Analysis, Anticancer, and …

P Barwa, S Asija, Y Deswal, D Kumar… - Applied …, 2025 - Wiley Online Library
The exploration of diorganotin (IV) compounds as potential inhibitors of cancer cell growth is
gaining attention. Here, we have emphasized the potential of diorganotin derivatives as …

Monomeric copper (II) complexes with unsymmetrical salen environment: Synthesis, characterization and study of biological activities

D Mohapatra, SA Patra, PD Pattanayak, G Sahu… - Journal of Inorganic …, 2024 - Elsevier
Three new ONNO-donor tetradentate unsymmetrical salen ligands were synthesized by
using o-phenyl diamine with substituted salicylaldehydes followed by a two-step reaction …