Cultivated crustacean meat (CCM) is a means to create highly valued shrimp, lobster, and
crab products directly from stem cells, thus removing the need to farm or fish live animals …

PARP-1 is rapidly recruited and activated by DNA double-strand breaks (DSBs). Upon
activation, PARP-1 synthesizes a structurally complex polymer composed of ADP-ribose …

Abstract Background The Random Forest (RF) algorithm for supervised machine learning is
an ensemble learning method widely used in science and many other fields. Its popularity …

A robust method for simultaneous visualization of all four cell cycle phases in living cells is
highly desirable. We developed an intensiometric reporter of the transition from S to G2 …

The dentition is critical to animal survival and teeth are present in modern vertebrates
including teleost fish, sharks, amphibians, mammals and reptiles. The developmental …

Microglia are the resident tissue macrophages of the central nervous system including the
retina. Under pathophysiological conditions, microglia can signal to Müller cells, the major …

Understanding and predicting the outcome of the interaction of light with DNA has a
significant impact on the study of DNA repair and radiotherapy. We report on a combination …

The inner ear sensory epithelia contain mechanosensitive hair cells and supporting cells.
Both cell types arise from SOX2-expressing prosensory cells, but the mechanisms …

Knee osteoarthritis is a chronic joint disease mainly characterized by cartilage degeneration.
The treatment is challenging due to the lack of blood vessels and nerve supplies in …

Elucidating the dynamics of DNA repair proteins is essential to understanding the
mechanisms that preserve genomic stability and prevent carcinogenesis. However, the …