A review on advancements in feature selection and feature extraction for high-dimensional NGS data analysis
Recent advancements in biomedical technologies and the proliferation of high-dimensional
Next Generation Sequencing (NGS) datasets have led to significant growth in the bulk and …
Next Generation Sequencing (NGS) datasets have led to significant growth in the bulk and …
PDGFRα+ ITGA11+ fibroblasts foster early-stage cancer lymphovascular invasion and lymphatic metastasis via ITGA11-SELE interplay
H Zheng, M An, Y Luo, X Diao, W Zhong, M Pang, Y Lin… - Cancer Cell, 2024 - cell.com
Cancer-associated fibroblasts (CAFs) exhibit considerable heterogeneity in advanced
cancers; however, the functional annotation and mechanism of CAFs in early-stage cancers …
cancers; however, the functional annotation and mechanism of CAFs in early-stage cancers …
Artificial Intelligence in Point-of-Care Biosensing: Challenges and Opportunities
The integration of artificial intelligence (AI) into point-of-care (POC) biosensing has the
potential to revolutionize diagnostic methodologies by offering rapid, accurate, and …
potential to revolutionize diagnostic methodologies by offering rapid, accurate, and …
Multi‑omics identification of a signature based on malignant cell-associated ligand–receptor genes for lung adenocarcinoma
S Xu, X Chen, H Ying, J Chen, M Ye, Z Lin, X Zhang… - BMC cancer, 2024 - Springer
Purpose Lung adenocarcinoma (LUAD) significantly contributes to cancer-related mortality
worldwide. The heterogeneity of the tumor immune microenvironment in LUAD results in …
worldwide. The heterogeneity of the tumor immune microenvironment in LUAD results in …
Effector memory–type regulatory T cells display phenotypic and functional instability
DJ Wendering, L Amini, S Schlickeiser… - Science …, 2024 - science.org
Regulatory T cells (Treg cells) hold promise for sustainable therapy of immune disorders.
Recent advancements in chimeric antigen receptor development and genome editing aim to …
Recent advancements in chimeric antigen receptor development and genome editing aim to …
Comprehensive application of AI algorithms with TCR NGS data for glioma diagnosis
K Zhou, Z **ao, Q Liu, X Wang, J Huo, X Wu, X Zhao… - Scientific Reports, 2024 - nature.com
T-cell receptor (TCR) detection can examine the extent of T-cell immune responses.
Therefore, the article analyzed characteristic data of glioma obtained by DNA-based TCR …
Therefore, the article analyzed characteristic data of glioma obtained by DNA-based TCR …
The effect of data transformation on low-dimensional integration of single-cell RNA-seq
Background Recent developments in single-cell RNA sequencing have opened up a
multitude of possibilities to study tissues at the level of cellular populations. However, the …
multitude of possibilities to study tissues at the level of cellular populations. However, the …
Identifying genetic signatures from single-cell rna sequencing data by matrix imputation and reduced set gene clustering
In this current era, the identification of both known and novel cell types, the representation of
cells, predicting cell fates, classifying various tumor types, and studying heterogeneity in …
cells, predicting cell fates, classifying various tumor types, and studying heterogeneity in …
[HTML][HTML] Single-nuclei RNA sequencing uncovers heterogenous transcriptional signatures in Parkinson's disease associated with nuclear receptor-related factor 1 …
PA Kambey, WY Liu, J Wu, B Bosco… - Neural Regeneration …, 2023 - journals.lww.com
Previous studies have found that deficiency in nuclear receptor-related factor 1 (Nurr1),
which participates in the development, differentiation, survival, and degeneration of …
which participates in the development, differentiation, survival, and degeneration of …
Detailed social network interactions and gut microbiome strain-sharing within isolated Honduras villages
When humans assemble into face-to-face social networks, they create an extended
environment that permits exposure to the microbiome of other members of a population …
environment that permits exposure to the microbiome of other members of a population …