Phage lysis: multiple genes for multiple barriers

J Cahill, R Young - Advances in virus research, 2019 - Elsevier
The first steps in phage lysis involve a temporally controlled permeabilization of the
cytoplasmic membrane followed by enzymatic degradation of the peptidoglycan. For …

Phage lysis: three steps, three choices, one outcome

R Young - Journal of microbiology, 2014 - Springer
The lysis of bacterial hosts by double-strand DNA bacteriophages, once thought to reflect
merely the accumulation of sufficient lysozyme activity during the infection cycle, has been …

[HTML][HTML] Short prokaryotic Argonaute systems trigger cell death upon detection of invading DNA

B Koopal, A Potocnik, SK Mutte, C Aparicio-Maldonado… - Cell, 2022 - cell.com
Argonaute proteins use single-stranded RNA or DNA guides to target complementary
nucleic acids. This allows eukaryotic Argonaute proteins to mediate RNA interference and …

Holins: the protein clocks of bacteriophage infections

IN Wang, DL Smith, R Young - Annual Reviews in Microbiology, 2000 - annualreviews.org
▪ Abstract Two proteins, an endolysin and a holin, are essential for host lysis by
bacteriophage. Endolysin is the term for muralytic enzymes that degrade the cell wall; …

Phages will out: strategies of host cell lysis

RY Young, N Wang, WD Roof - Trends in microbiology, 2000 - cell.com
Most phages accomplish host lysis using a muralytic enzyme, or endolysin, and a holin,
which permeabilizes the membrane at a programmed time and thus controls the length of …

Prevalence and evolution of core photosystem II genes in marine cyanobacterial viruses and their hosts

MB Sullivan, D Lindell, JA Lee, LR Thompson… - PLoS …, 2006 - journals.plos.org
Cyanophages (cyanobacterial viruses) are important agents of horizontal gene transfer
among marine cyanobacteria, the numerically dominant photosynthetic organisms in the …

Lysis timing and bacteriophage fitness

IN Wang - Genetics, 2006 - academic.oup.com
The effect of lysis timing on bacteriophage (phage) fitness has received little theoretical or
experimental attention. Previously, the impact of lysis timing on phage fitness was studied …

Bacteriophage adsorption: Likelihood of virion encounter with bacteria and other factors affecting rates

ST Abedon - Antibiotics, 2023 - mdpi.com
For ideal gasses, the likelihood of collision of two molecules is a function of concentrations
as well as environmental factors such as temperature. This too is the case for particles …

Bacteriophage latent-period evolution as a response to resource availability

ST Abedon, TD Herschler, D Stopar - Applied and environmental …, 2001 - Am Soc Microbiol
Bacteriophages (phages) modify microbial communities by lysing hosts, transferring genetic
material, and effecting lysogenic conversion. To understand how natural communities are …

[HTML][HTML] Bacteriophage-encoded enzymes destroying bacterial cell membranes and walls, and their potential use as antimicrobial agents

Ł Grabowski, K Łepek, M Stasiłojć… - Microbiological …, 2021 - Elsevier
Appearance of pathogenic bacteria resistant to most, if not all, known antibiotics is currently
one of the most significant medical problems. Therefore, development of novel antibacterial …