Role of core circadian clock genes in hormone release and target tissue sensitivity in the reproductive axis

A Sen, HM Hoffmann - Molecular and cellular endocrinology, 2020 - Elsevier
Precise timing in hormone release from the hypothalamus, the pituitary and ovary is critical
for fertility. Hormonal release patterns of the reproductive axis are regulated by a feedback …

Central circadian control of female reproductive function

BH Miller, JS Takahashi - Frontiers in endocrinology, 2014 - frontiersin.org
Over the past two decades, it has become clear just how much of our physiology is under the
control of the suprachiasmatic nucleus (SCN) and the cell-intrinsic molecular clock that ticks …

[책][B] Knobil and Neill's physiology of reproduction

TM Plant, AJ Zeleznik - 2014 - books.google.com
The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to
provide the historical context to current research, and most importantly as an aid for …

Coevolution of the spexin/galanin/kisspeptin family: Spexin activates galanin receptor type II and III

DK Kim, S Yun, GH Son, JI Hwang, CR Park… - …, 2014 - academic.oup.com
The novel neuropeptide spexin (SPX) was discovered using bioinformatics. The function of
this peptide is currently under investigation. Here, we identified SPX along with a second …

A microRNA switch regulates the rise in hypothalamic GnRH production before puberty

A Messina, F Langlet, K Chachlaki, J Roa… - Nature …, 2016 - nature.com
A sparse population of a few hundred primarily hypothalamic neurons forms the hub of a
complex neuroglial network that controls reproduction in mammals by secreting the'master …

Circadian rhythms within the female HPG axis: from physiology to etiology

S Shao, H Zhao, Z Lu, X Lei, Y Zhang - Endocrinology, 2021 - academic.oup.com
Declining female fertility has become a global health concern. It results partially from an
abnormal circadian clock caused by unhealthy diet and sleep habits in modern life. The …

GnRH and the photoperiodic control of seasonal reproduction: Delegating the task to kisspeptin and RFRP‐3

H Dardente, V Simonneaux - Journal of neuroendocrinology, 2022 - Wiley Online Library
Synchronization of mammalian breeding activity to the annual change of photoperiod and
environmental conditions is of the utmost importance for individual survival and species …

Hypothalamus as an endocrine organ

IJ Clarke - Comprehensive Physiology, 2011 - Wiley Online Library
The endocrine hypothalamus constitutes those cells which project to the median eminence
and secrete neurohormones into the hypophysial portal blood to act on cells of the anterior …

A Kiss to drive rhythms in reproduction

V Simonneaux - European Journal of Neuroscience, 2020 - Wiley Online Library
Reproduction, like many other biological functions, exhibits marked daily and seasonal
rhythms in order to anticipate and adapt breeding activity to environmental challenges. In …

Novel insights into minipuberty and GnRH: Implications on neurodevelopment, cognition, and COVID‐19 therapeutics

K Chachlaki, K Le Duc, L Storme… - Journal of …, 2024 - Wiley Online Library
In humans, the first 1000 days of life are pivotal for brain and organism development. Shortly
after birth, gonadotropin‐releasing hormone (GnRH) neurons in the hypothalamus are …