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Nanoparticles in drug delivery: From history to therapeutic applications
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …
The uniqueness of albumin as a carrier in nanodrug delivery
Albumin is an appealing carrier in nanomedicine because of its unique features. First, it is
the most abundant protein in plasma, endowing high biocompatibility, biodegradability …
the most abundant protein in plasma, endowing high biocompatibility, biodegradability …
[HTML][HTML] Anticancer drugs: recent strategies to improve stability profile, pharmacokinetic and pharmacodynamic properties
G Ioele, M Chieffallo, MA Occhiuzzi, M De Luca… - Molecules, 2022 - mdpi.com
In past decades, anticancer research has led to remarkable results despite many of the
approved drugs still being characterized by high systemic toxicity mainly due to the lack of …
approved drugs still being characterized by high systemic toxicity mainly due to the lack of …
The development of human serum albumin-based drugs and relevant fusion proteins for cancer therapy
H Tao, R Wang, W Sheng, Y Zhen - International journal of biological …, 2021 - Elsevier
Human serum albumin (HSA)-based therapeutics have attracted tremendous attention in the
development of anticancer agents. The versatile properties of HSA make HSA-based …
development of anticancer agents. The versatile properties of HSA make HSA-based …
Injectable thermosensitive hydrogel containing erlotinib‐loaded hollow mesoporous silica nanoparticles as a localized drug delivery system for NSCLC therapy
X Zhou, X He, K Shi, L Yuan, Y Yang, Q Liu… - Advanced …, 2020 - Wiley Online Library
Erlotinib (ERT), oral administration agents, is one of the most pivotal targeted drugs in the
treatment of non‐small cell lung cancer (NSCLC); however, its poor solubility, low oral …
treatment of non‐small cell lung cancer (NSCLC); however, its poor solubility, low oral …
HER2‐positive breast cancer brain metastasis: a new and exciting landscape
AS Zimmer, AED Van Swearingen… - Cancer …, 2022 - Wiley Online Library
Abstract Background Brain metastases (BrM) incidence is 25% to 50% in women with
advanced human epidermal growth factor receptor 2 (HER2)‐positive breast cancer …
advanced human epidermal growth factor receptor 2 (HER2)‐positive breast cancer …
CDKN2A-mediated molecular subtypes characterize the hallmarks of tumor microenvironment and guide precision medicine in triple-negative breast cancer
Currently, breast cancer (BRCA) has become the most common cancer in the world, whose
pathological mechanism is complex. Among its subtypes, triple-negative breast cancer …
pathological mechanism is complex. Among its subtypes, triple-negative breast cancer …
Engineered bacteria enhance immunotherapy and targeted therapy through stromal remodeling of tumors
Desmoplastic solid tumors are characterized by the rapid build‐up of extracellular matrix
(ECM) macromolecules, such as hyaluronic acid (HA). The resulting physiological barrier …
(ECM) macromolecules, such as hyaluronic acid (HA). The resulting physiological barrier …
Triple negative breast cancer: shedding light onto the role of pi3k/akt/mtor pathway
D Massihnia, A Galvano, D Fanale, A Perez… - …, 2016 - pmc.ncbi.nlm.nih.gov
Breast cancer is one of the most widespread carcinoma and one of the main causes of
cancer-related death worldwide, especially in women aged between 35 and 75 years …
cancer-related death worldwide, especially in women aged between 35 and 75 years …
Albumin-based cancer therapeutics for intraperitoneal drug delivery: a review
Albumin is a remarkable carrier protein with multiple cellular receptor and ligand binding
sites, which are able to bind and transport numerous endogenous and exogenous …
sites, which are able to bind and transport numerous endogenous and exogenous …