Epidemiological studies have consistently demonstrated the benefits of dietary fibre on
gastrointestinal health through consumption of unrefined whole foods, such as wholegrains …

Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …

Autoimmune diseases, including inflammatory bowel disease, multiple sclerosis and
rheumatoid arthritis, have distinct clinical presentations but share underlying patterns of gut …

Diet is a major factor that shapes the gut microbiome, but the consequences of diet-induced
changes in the microbiome for host pathophysiology remain poorly understood. We …

Microbiome data, metadata and analytical workflows have become 'big'in terms of volume
and complexity. Although the infrastructure and technologies to share data have been …

The oral microbiome plays key roles in human biology, health, and disease, but little is
known about the global diversity, variation, or evolution of this microbial community. To …

Type 2 diabetes mellitus (T2DM) is a disease that affects over 9% of the United States
population and is closely linked to obesity. While obesity was once thought to stem from a …

Background A higher intake of dietary fiber is associated with a decreased risk of chronic
inflammatory diseases such as cardiovascular disease and inflammatory bowel disease …

Overweight, obesity, undernutrition and their respective sequelae have devastating tolls on
personal and public health worldwide. Traditional approaches for treating these conditions …

Since 1980, obesity prevalence among US adults has soared from 14% to 42%. The
commonly accepted explanation is pervasive overeating: ever-increasing energy intake as …