Glioma and cerebral ischemic stroke are two major events that lead to patient death
worldwide. Although these conditions have different physiological incidences,~ 10% of …

Stroke is a debilitating condition which is also the second leading cause of death and
disability worldwide. Despite the benefits and promises shown by numerous neuroprotective …

Background and Purpose Aquaporin-4 (AQP4) is an abundant water channel protein in
brain that regulates water transport to maintain homeostasis. Cerebral edema resulting from …

Panels from Figures 2a and 3a appear similar to panels from Figures 2A and 3A of the
article that the authors et al. have previously published in PLoS One 8 (9)(2013) e73481 …

Degenerative diseases often strike older adults and are characterized by progressive
deterioration of cells, eventually leading to tissue and organ degeneration for which limited …

Abstract Aquaporin 4 (AQP4) is the major water channel expressed in the central nervous
system (CNS), and it is primarily expressed in astrocytes. It has been studied in various brain …

Cerebral edema often manifests after the development of cerebrovascular disease,
particularly in the case of stroke, both ischemic and hemorrhagic. Without clinical …

Current experimental evidence points to the conclusion that aquaporin 4 (AQP4), which is
an important water-channel membrane protein found in the brain, could play major roles in …

Acid-sensing ion channel 1a (ASIC1a) is a member of the extracellular H+-activated cation
channels family. Our previous studies suggested that ASIC1a contributed to acid-induced rat …

Matrix metalloproteinases are zinc-containing endopeptidases that are involved in
extracellular matrix (ECM) remodeling cascade in many neurological disorders, including …