Abstract Each year, the American Cancer Society publishes a summary of its guidelines for
early cancer detection, data and trends in cancer screening rates, and select issues related …

Colorectal cancer (CRC) disproportionately affects people from low socioeconomic
backgrounds and some racial minorities. Disparities in CRC incidence and outcomes might …

Background Colorectal cancer is the third most diagnosed cancer in adults in the United
States. Early detection could prevent more than 90% of colorectal cancer–related deaths, yet …

Recent studies have revealed the critical roles of ferroptosis in different physiological and
pathological processes, however, its effects on the progression of colorectal cancer stem …

Screening, followed by colonoscopic polypectomy (or surgery for malignant lesions),
prevents incident colorectal cancer and mortality. However, there are variations in effective …

Background Biomarkers have revolutionized the management of colorectal cancer (CRC),
facilitating early detection, prevention, personalized treatment, and minimal residual disease …

Colorectal cancer stem cells (CCSCs) play important roles in the prognosis,
chemoresistance, and treatment failure of colorectal cancer (CRC). Ferroptosis is an …

Gilbertson first suggested in the 1960s that colorectal cancer (CRC) may arise from
intermediary lesions in the colon. 1 Subsequent studies demonstrated foci of …

Background Detection of circulating tumor DNA (ctDNA) is a minimally invasive and
convenient blood-based screening strategy that may increase effectiveness of colorectal …

Background & Aims Colorectal cancer (CRC) incidence has decreased overall in the last
several decades, but it has increased among younger adults. Prior studies have …