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Multicellular tumor spheroids: a relevant 3D model for the in vitro preclinical investigation of polymer nanomedicines
The application of nanotechnology to medicine, usually termed nanomedicine, has given a
crucial impulse to the design of various drug-loaded nanocarriers driven by the aim to …
crucial impulse to the design of various drug-loaded nanocarriers driven by the aim to …
Biomaterials for three-dimensional cell culture: From applications in oncology to nanotechnology
Three-dimensional cell culture has revolutionized cellular biology research and opened the
door to novel discoveries in terms of cellular behavior and response to microenvironment …
door to novel discoveries in terms of cellular behavior and response to microenvironment …
Light sheet fluorescence microscopy versus confocal microscopy: in quest of a suitable tool to assess drug and nanomedicine penetration into multicellular tumor …
We recently constructed a multicellular spheroid model of pancreatic tumor based on a triple
co-culture of cancer cells, fibroblasts and endothelial cells and characterized by the …
co-culture of cancer cells, fibroblasts and endothelial cells and characterized by the …
Meet me halfway: Are in vitro 3D cancer models on the way to replace in vivo models for nanomedicine development?
The complexity and diversity of the biochemical processes that occur during tumorigenesis
and metastasis are frequently over-simplified in the traditional in vitro cell cultures. Two …
and metastasis are frequently over-simplified in the traditional in vitro cell cultures. Two …
Nanoparticles for advanced photodynamic therapy of cancer
Background: The world widespread rise in cancer incidence has caused an increase in the
demand for effective and safe materials for treatment. One of the most prevalent forms of …
demand for effective and safe materials for treatment. One of the most prevalent forms of …
Photodynamic therapy in 3D cancer models and the utilisation of nanodelivery systems
Photodynamic therapy (PDT) is the subject of considerable research in experimental cancer
models mainly for the treatment of solid cancerous tumours. Recent studies on the use of …
models mainly for the treatment of solid cancerous tumours. Recent studies on the use of …
[HTML][HTML] Nanoparticle-mediated delivery systems in photodynamic therapy of colorectal cancer
Colorectal cancer (CRC) involving a malignant tumour remains one of the greatest
contributing causes of fatal mortality and has become the third globally ranked malignancy …
contributing causes of fatal mortality and has become the third globally ranked malignancy …
Effects of plasma activated medium on head and neck FaDu cancerous cells: Comparison of 3D and 2D response
Objective: The aim of this work is to investigate the inhibitory effect of Plasma Activated
Medium (PAM) on Head and Neck cancerous cells (FaDu). The response of FaDu cells in …
Medium (PAM) on Head and Neck cancerous cells (FaDu). The response of FaDu cells in …
Synthesis and Self-Assembly of UV-Cross-Linkable Amphiphilic Polyoxazoline Block Copolymers: Importance of Multitechnique Characterization
In the nanomedicine field, there is a need to widen the availability of nanovectors to
compensate for the increasingly reported side effects of poly (ethene glycol). Nanovectors …
compensate for the increasingly reported side effects of poly (ethene glycol). Nanovectors …
Role of polymer micelles in the delivery of photodynamic therapy agent to liposomes and cells
The use of nanocarriers for hydrophobic photosensitizers, in the context of photodynamic
therapy (PDT) to improve pharmacokinetics and bio-distribution, is well-established …
therapy (PDT) to improve pharmacokinetics and bio-distribution, is well-established …