An overview on the synthesis of fused pyridocoumarins with biological interest
MD Douka, KE Litinas - Molecules, 2022 - mdpi.com
Pyridocoumarins are a class of synthetic and naturally occurring organic compounds with
interesting biological activities. This review focuses on the synthetic strategies for the …
interesting biological activities. This review focuses on the synthetic strategies for the …
[PDF][PDF] Synthesis and anticancer activities of thiazoles, 1, 3-thiazines, and thiazolidine using chitosan-grafted-poly (vinylpyridine) as basic catalyst
Three different series of ethylidenehydrazonothiazoles 5a-c, 6a-c, ethylidenehydrazono-1, 3-
thiazines 9a-i and ethylidenehydrazonothiazolidine 12 have been prepared via reactions of …
thiazines 9a-i and ethylidenehydrazonothiazolidine 12 have been prepared via reactions of …
Acetylcoumarin in cyclic and heterocyclic-containing coumarins: Synthesis and biological applications
In design and development of bioactive compounds, coumarins as ubiquitous natural
heterocyclic compounds have been widely used. In particular, the combination of the …
heterocyclic compounds have been widely used. In particular, the combination of the …
Three-component synthesis of some new coumarin derivatives as anticancer agents
A three-component reaction for the synthesis of novel 3-heteroaryl-coumarin utilizing
acetylcoumarin synthon under ultrasonic irradiation was developed using chitosan-grafted …
acetylcoumarin synthon under ultrasonic irradiation was developed using chitosan-grafted …
Synthesis, molecular docking study, and cytotoxic activity against MCF cells of new Thiazole–Thiophene scaffolds
Investigating novel compounds that may be useful in designing new, less toxic, selective,
and potent breast anticancer agents is still the main challenge for medicinal chemists. Thus …
and potent breast anticancer agents is still the main challenge for medicinal chemists. Thus …
A facile access and evaluation of some novel thiazole and 1, 3, 4-thiadiazole derivatives incorporating thiazole moiety as potent anticancer agents
Background Many heterocyclic compounds containing thiazole or 1, 3, 4-thiadiazole ring in
their skeletons have been reported to possess various pharmacological activities especially …
their skeletons have been reported to possess various pharmacological activities especially …
Multicomponent synthesis, DFT calculations and molecular docking studies of novel thiazolyl-pyridazinones as potential antimicrobial agents against antibiotic …
S Abu-Melha, ZA Muhammad, AS Abouzid… - Journal of Molecular …, 2021 - Elsevier
Novel series of aryl (hetaryl) thiazolylpyridazinedione derivatives were synthesized via one-
pot three-component synthesis of maleic anhydride, thiosemicarbazide and the appropriate …
pot three-component synthesis of maleic anhydride, thiosemicarbazide and the appropriate …
Heterocyclisation of 2, 5-diacetyl-3, 4-disubstituted-thieno [2, 3-b] thiophene bis-thiosemicarbazones leading to bis-thiazoles and bis-1, 3, 4-thiadiazoles as anti-breast …
SM Gomha, MG Badrey… - Journal of Chemical …, 2016 - journals.sagepub.com
In this paper, the synthesis of bis-thiazoles and bis-1, 3, 4-thiadiazoles linked to a
thienothiophene nucleus is described. The synthesis was achieved through interaction …
thienothiophene nucleus is described. The synthesis was achieved through interaction …
[PDF][PDF] Synthesis and antitumor activity of 1, 3, 4-thiadiazole derivatives bearing coumarine ring
SM Gomha, HM Abdel-aziz - Heterocycles, 2015 - triggered.stanford.clockss.org
In the present study, preparation of a novel series of N'-(3, 5-diphenyl-1, 3, 4-thiadiazol-2
(3H)-ylidene)-2-oxo-2H-chromene-3-carbohydrazide (8a-m) was prepared by two methods …
(3H)-ylidene)-2-oxo-2H-chromene-3-carbohydrazide (8a-m) was prepared by two methods …
The Chromenopyridine Scaffold: A Privileged Platform in Drug Design
F Pedroso de Lima, M Costa, A Sousa, MF Proença - Molecules, 2024 - mdpi.com
The chromenopyridine scaffold represents an important class of heterocyclic compounds
exhibiting a broad spectrum of biological properties. This review describes novel and …
exhibiting a broad spectrum of biological properties. This review describes novel and …