Adaptive laboratory evolution (ALE) has long been used as the tool of choice for microbial
engineering applications, ranging from the production of commodity chemicals to the …

This work presents an omics-driven modeling pipeline that integrates machine-learning
tools to facilitate the dynamic modeling of multiscale biological systems. Random forests and …

Due to metabolic engineering advances, it is possible to produce a large number of bio-
based chemical compounds. However, the downstream processing is challenging the …

Modeling in biology has given valuable insights and can be a guide for wet labs. The
optimal prediction of a particular metabolite can be obtained by analyzing the genome-scale …

Autotrophic microorganisms convert CO2 into biomass using energy from light or from the
oxidation of inorganic molecules. When implementing biosynthetic pathways for the …

Succinic acid is a versatile platform chemical. It can be used as a building block for the
synthesis of a wide range of products, including biodegradable plastics such as …