Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation

I Galve-Roperh, V Chiurchiù, J Díaz-Alonso… - Progress in lipid …, 2013 - Elsevier
Cannabinoids, the active components of cannabis (Cannabis sativa) extracts, have attracted
the attention of human civilizations for centuries, much earlier than the discovery and …

Targeting cannabinoid signaling in the immune system:“High”-ly exciting questions, possibilities, and challenges

A Oláh, Z Szekanecz, T Bíró - Frontiers in Immunology, 2017 - frontiersin.org
It is well known that certain active ingredients of the plants of Cannabis genus, ie, the
“phytocannabinoids”[pCBs; eg,(−)-trans-Δ9-tetrahydrocannabinol (THC),(−)-cannabidiol …

Cannabinoid exposure during pregnancy and its impact on immune function

C Dong, J Chen, A Harrington, KY Vinod… - Cellular and Molecular …, 2019 - Springer
Cannabinoids are the most commonly abused illicit drugs worldwide. While cannabis can be
beneficial for certain heath conditions, abuse of potent synthetic cannabinoids has been on …

Effects of cannabinoids on T-cell function and resistance to infection

TK Eisenstein, JJ Meissler - Journal of Neuroimmune Pharmacology, 2015 - Springer
This review examines the effects of cannabinoids on immune function, with a focus on
effects on T-cells, as well as on resistance to infection. The paper considers the immune …

Immunoregulatory role of cannabinoids during infectious disease

R Hernández-Cervantes, M Méndez-Díaz… - …, 2018 - karger.com
Although the endocannabinoid system (ECS) is involved in the regulation of several
physiological processes, including sleep and the immune response, its role during infections …

Cannabinoids and inflammation: implications for people living with HIV

CT Costiniuk, MA Jenabian - Aids, 2019 - journals.lww.com
Thanks to the success of modern antiretroviral therapy (ART), people living with HIV (PLWH)
have life expectancies which approach that of persons in the general population. However …

Cortical neuroinflammation contributes to long-term cognitive dysfunctions following adolescent delta-9-tetrahydrocannabinol treatment in female rats

E Zamberletti, M Gabaglio, P Prini, T Rubino… - European …, 2015 - Elsevier
Over 180 million people consume cannabis globally. Cannabis use peaks during
adolescence with a trend for continued consumption by adults. Notably, several studies …

The role of CB1 in immune modulation by cannabinoids

BLF Kaplan - Pharmacology & therapeutics, 2013 - Elsevier
There is clear evidence that CB2, historically referred to as the peripheral cannabinoid
receptor, mediates many of the immune modulatory effects of cannabinoids. However …

The immune endocannabinoid system of the tumor microenvironment

M Kienzl, J Kargl, R Schicho - International Journal of Molecular Sciences, 2020 - mdpi.com
Leukocytes are part of the tumor microenvironment (TME) and are critical determinants of
tumor progression. Because of the immunoregulatory properties of cannabinoids, the …

Histone modifications are associated with Δ9-tetrahydrocannabinol-mediated alterations in antigen-specific T cell responses

X Yang, VL Hegde, R Rao, J Zhang… - Journal of Biological …, 2014 - jbc.org
Marijuana is one of the most abused drugs due to its psychotropic effects. Interestingly, it is
also used for medicinal purposes. The main psychotropic component in marijuana, Δ 9 …