While medicinal inorganic chemistry has been practised for over 5000 years, it was not until
the late 1800s when Alfred Werner published his ground-breaking research on coordination …

The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two
nitrogen atoms, is an important functional fragment widely present in a large number of …

Current platinum-based drugs used in chemotherapy, like cisplatin and its derivatives, are
greatly limited due to side-effects and drug resistance. This has inspired the search for novel …

N-Heterocyclic carbenes (NHCs) have been introduced as a new platform for the
development of anticancer metal complexes for several decades. NHCs as strong σ-donors …

Organometallic compounds currently occupy an important place in the field of medicinal
inorganic chemistry due to the unique chemical properties of metal coordination …

A series of organometallic AuI N‐heterocyclic carbene (NHC) complexes was synthesized
and characterized for anticancer activity in four human cancer cell lines. The compounds' …

Herein, we present a comparative study on the chemistry and biological activity of N-
heterocyclic carbene (NHC) Pt (II)/Au (I) complexes. Accordingly, representative compounds …

Reaction of two equivalents of the bulky 1, 3-bis (2, 6-diethylphenyl) thiourea ligand (L) with
MX (being M= Cu+, Ag+; and X= Cl−, Br−, I−) in acetonitrile afforded neutral complexes of …

We report 15 new Cu (II) complexes with tridentate NNO β-acylenamino ligands derived
from 2-picolylamine and bearing up to three alkyl, alkoxy, alkoxycarbonyl, or (pseudo) halide …

In the last 20 years, N-Heterocyclic Carbene (NHC) ligands have been ubiquitous in
biological and medicinal chemistry. Part of their success lies in the tremendous number of …