Lipid-based nanoformulations in the treatment of neurological disorders
The neurological disorders affect millions of people worldwide, and are bracketed as the
foremost basis of disability-adjusted life years (DALYs). The treatment options are …
foremost basis of disability-adjusted life years (DALYs). The treatment options are …
Targeted delivery of miRNA based therapeuticals in the clinical management of Glioblastoma Multiforme
Glioblastoma multiforme (GBM) is the most aggressive (WHO grade IV) form of diffuse
glioma endowed with tremendous invasive capacity. The availability of narrow therapeutic …
glioma endowed with tremendous invasive capacity. The availability of narrow therapeutic …
QbD-driven formulation development and evaluation of topical hydrogel containing ketoconazole loaded cubosomes
The proposed study aimed to develop topical hydrogel containing ketoconazole loaded
cubosomes with lower surfactant concentrations using the 'Quality by Design'(QbD) …
cubosomes with lower surfactant concentrations using the 'Quality by Design'(QbD) …
Application of design of experiments (DoE) in pharmaceutical product and process optimization
The development of pharmaceutical drug products involves a multitude of functional and
nonfunctional excipients, a series of processes, and manufacturing steps. Hence, the …
nonfunctional excipients, a series of processes, and manufacturing steps. Hence, the …
Development of transethosomes formulation for dermal fisetin delivery: Box–Behnken design, optimization, in vitro skin penetration, vesicles–skin interaction and …
The present study was conducted for the optimization of transethosomes formulation for
dermal fisetin delivery. The optimization of the formulation was carried out using “Box …
dermal fisetin delivery. The optimization of the formulation was carried out using “Box …
Bioinspired nanocomposites: applications in disease diagnosis and treatment
Recent advancement in the field of synthesis and application of nanomaterials provided
holistic approach for both diagnosis as well as treatment of diseases. Briefly, three …
holistic approach for both diagnosis as well as treatment of diseases. Briefly, three …
[HTML][HTML] Quality by design (QbD) in the formulation and optimization of liquid crystalline nanoparticles (LCNPs): A risk based industrial approach
The intersection of lipid-based nanoparticles and lyotropic liquid crystals has provided a
novel type of nanocarrier system known as 'lipid-based lyotropic liquid crystals' or 'liquid …
novel type of nanocarrier system known as 'lipid-based lyotropic liquid crystals' or 'liquid …
Development and optimization of transethosomal gel of apigenin for topical delivery: In-vitro, ex-vivo and cell line assessment
The main aim of this study was to optimize the transethosomes of apigenin formulated by the
thin film hydration method using surfactant Span 80. Response surface Box-Behnken design …
thin film hydration method using surfactant Span 80. Response surface Box-Behnken design …
Carbon allotropes-based nanodevices: graphene in biomedical applications
Carbon is the most abundant and structural building-block element of life. It is nonmetallic,
but bears the unique ability of self-binding and associating other elements to form …
but bears the unique ability of self-binding and associating other elements to form …
Optimization and characterization of rivastigmine nanolipid carrier loaded transdermal patches for the treatment of dementia
The present study aimed to develop nanolipid carrier (NLC) loaded transdermal system of
rivastigmine for bioavailability enhancement. NLC was optimized using Box-Behnken …
rivastigmine for bioavailability enhancement. NLC was optimized using Box-Behnken …