Extracellular vesicles (EVs) shed by neurons and glia in the central nervous system carry a
cargo of specific bioactive molecules, facilitating intercellular communication. However, in …

Huntington's disease (HD) is a rare hereditary autosomal dominant neurodegenerative
disorder, which is caused by expression of mutant huntingtin protein (mHTT) with an …

This virtual workshop was convened by the National Heart, Lung, and Blood Institute, in
partnership with the Office of Strategic Coordination of the Office of the National Institutes of …

Neural progenitor cells (NPCs) of the subventricular zone proliferate in response to ischemic
stroke in the adult mouse brain. Newly generated cells have been considered to influence …

Discovering effective therapies is difficult for neurological and developmental disorders in
that disease progression is often associated with a complex and interactive mechanism …

In the era of multi-omic sciences, dogma on singular cause-effect in physio-pathological
processes is overcome and system biology approaches have been providing new …

Extracellular vesicles (EVs) have garnered significant interest in the field of biomedical
science due to their potential applications in therapy and diagnosis. These vesicles …

Proteinopathies are a large group of neurodegenerative diseases caused by both genetic
and sporadic mutations in particular genes which can lead to alterations of the protein …

Endothelial cells are constantly exposed to environmental stress factors that, above a certain
threshold, trigger cellular senescence and apoptosis. The altered vascular function affects …

Parkinson's disease (PD) is the second most frequent neurodegenerative disorder, and
autophagy dysfunction is involved in the pathogenesis of PD. Mesenchymal stem cells …