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[HTML][HTML] Crimean-Congo hemorrhagic fever virus: current advances and future prospects of antiviral strategies
S Dai, F Deng, H Wang, Y Ning - Viruses, 2021 - mdpi.com
Crimean-Congo hemorrhagic fever virus (CCHFV) is a widespread, tick-borne pathogen that
causes Crimean-Congo hemorrhagic fever (CCHF) with high morbidity and mortality …
causes Crimean-Congo hemorrhagic fever (CCHF) with high morbidity and mortality …
[HTML][HTML] Structural elucidation of SARS-CoV-2 vital proteins: Computational methods reveal potential drug candidates against main protease, Nsp12 polymerase and …
Recently emerged SARS-CoV-2 caused a major outbreak of coronavirus disease 2019
(COVID-19) and instigated a widespread fear, threatening global health safety. To date, no …
(COVID-19) and instigated a widespread fear, threatening global health safety. To date, no …
[HTML][HTML] Promising terpenes as SARS-CoV-2 spike receptor-binding domain (RBD) attachment inhibitors to the human ACE2 receptor: Integrated computational …
The spike protein receptor binding domain (S-RBD) is a necessary corona-viral protein for
binding and entry of coronaviruses (COVs) into the host cells. Hence, it has emerged as an …
binding and entry of coronaviruses (COVs) into the host cells. Hence, it has emerged as an …
In silico design and analyses of a multi-epitope vaccine against Crimean-Congo hemorrhagic fever virus through reverse vaccinology and immunoinformatics …
Abstract Crimean Congo Hemorrhagic Fever virus (CCHFV) is a deadly human pathogen
that causes an emerging zoonotic disease with a broad geographic spread, especially in …
that causes an emerging zoonotic disease with a broad geographic spread, especially in …
Development of a novel multi-epitope vaccine against crimean-congo hemorrhagic fever virus: An integrated reverse vaccinology, vaccine informatics and biophysics …
Crimean-Congo hemorrhagic fever (CCHF) is a highly severe and virulent viral disease of
zoonotic origin, caused by a tick-born CCHF virus (CCHFV). The virus is endemic in many …
zoonotic origin, caused by a tick-born CCHF virus (CCHFV). The virus is endemic in many …
[HTML][HTML] Discovery of human coronaviruses pan-papain-like protease inhibitors using computational approaches
The papain-like protease (PL pro) is vital for the replication of coronaviruses (CoVs), as well
as for esca** innate-immune responses of the host. Hence, it has emerged as an …
as for esca** innate-immune responses of the host. Hence, it has emerged as an …
In Vitro Antidiabetic, Anti-Obesity and Antioxidant Analysis of Ocimum basilicum Aerial Biomass and in Silico Molecular Docking Simulations with Alpha-Amylase and …
The present study explored phytochemicals, porcine pancreatic α-amylase (PPA) and lipase
(PPL) inhibitory activities and antioxidant potential of polar and nonpolar extracts of the …
(PPL) inhibitory activities and antioxidant potential of polar and nonpolar extracts of the …
[HTML][HTML] Protoplast Isolation and Shoot Regeneration from Protoplast-Derived Callus of Petunia hybrida Cv. Mirage Rose
Despite the increasing use of protoplasts in plant biotechnology research, shoot
regeneration from protoplasts remains challenging. In this study, we investigated the factors …
regeneration from protoplasts remains challenging. In this study, we investigated the factors …
[HTML][HTML] The discovery of Zika virus NS2B-NS3 inhibitors with antiviral activity via an integrated virtual screening approach
With expanding recent outbreaks and a lack of treatment options, the Zika virus (ZIKV) poses
a severe health concern. The availability of ZIKV NS2B-NS3 co-crystallized structures paved …
a severe health concern. The availability of ZIKV NS2B-NS3 co-crystallized structures paved …
Identification of novel human USP2 inhibitor and its putative role in treatment of COVID-19 by inhibiting SARS-CoV-2 papain-like (PLpro) protease
Human ubiquitin carboxyl-terminal hydrolase-2 (USP2) inhibitors, such as thiopurine
analogs, have been reported to inhibit SARS-CoV papain-like proteases (PLpro). The PLpro …
analogs, have been reported to inhibit SARS-CoV papain-like proteases (PLpro). The PLpro …