Control of satellite cell function in muscle regeneration and its disruption in ageing
P Sousa-Victor, L García-Prat… - … Reviews Molecular Cell …, 2022 - nature.com
Skeletal muscle contains a designated population of adult stem cells, called satellite cells,
which are generally quiescent. In homeostasis, satellite cells proliferate only sporadically …
which are generally quiescent. In homeostasis, satellite cells proliferate only sporadically …
Perspectives on skeletal muscle stem cells
F Relaix, M Bencze, MJ Borok, A Der Vartanian… - Nature …, 2021 - nature.com
Skeletal muscle has remarkable regeneration capabilities, mainly due to its resident muscle
stem cells (MuSCs). In this review, we introduce recently developed technologies and the …
stem cells (MuSCs). In this review, we introduce recently developed technologies and the …
Large-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration
Skeletal muscle repair is driven by the coordinated self-renewal and fusion of myogenic
stem and progenitor cells. Single-cell gene expression analyses of myogenesis have been …
stem and progenitor cells. Single-cell gene expression analyses of myogenesis have been …
Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis
G Coulis, D Jaime, C Guerrero-Juarez… - Science …, 2023 - science.org
Macrophages are essential for skeletal muscle homeostasis, but how their dysregulation
contributes to the development of fibrosis in muscle disease remains unclear. Here, we used …
contributes to the development of fibrosis in muscle disease remains unclear. Here, we used …
The inflammatory speech of fibroblasts
Activation of fibroblasts is a key event during normal tissue repair after injury and the
dysregulated repair processes that result in organ fibrosis. To most researchers, fibroblasts …
dysregulated repair processes that result in organ fibrosis. To most researchers, fibroblasts …
Fibro-adipogenic progenitors in skeletal muscle homeostasis, regeneration and diseases
Skeletal muscle possesses a remarkable regenerative capacity that relies on the activity of
muscle stem cells, also known as satellite cells. The presence of non-myogenic cells also …
muscle stem cells, also known as satellite cells. The presence of non-myogenic cells also …
Fibro–adipogenic progenitors cross-talk in skeletal muscle: the social network
Skeletal muscle is composed of a large and heterogeneous assortment of cell populations
that interact with each other to maintain muscle homeostasis and orchestrate regeneration …
that interact with each other to maintain muscle homeostasis and orchestrate regeneration …
Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury
Q Sastourné-Arrey, M Mathieu, X Contreras… - Nature …, 2023 - nature.com
Fibro-adipogenic progenitors (FAPs) play a crucial role in skeletal muscle regeneration, as
they generate a favorable niche that allows satellite cells to perform efficient muscle …
they generate a favorable niche that allows satellite cells to perform efficient muscle …
Temporal dynamics and heterogeneity of cell populations during skeletal muscle regeneration
Mammalian skeletal muscle possesses a unique ability to regenerate, which is primarily
mediated by a population of resident muscle stem cells (MuSCs) and requires a concerted …
mediated by a population of resident muscle stem cells (MuSCs) and requires a concerted …
The jam session between muscle stem cells and the extracellular matrix in the tissue microenvironment
M Loreti, A Sacco - NPJ Regenerative medicine, 2022 - nature.com
Skeletal muscle requires a highly orchestrated coordination between multiple cell types and
their microenvironment to exert its function and to maintain its homeostasis and regenerative …
their microenvironment to exert its function and to maintain its homeostasis and regenerative …