Psychotropic drug–related weight gain and its treatment

RS McIntyre, ATH Kwan, JD Rosenblat… - American Journal of …, 2024 - psychiatryonline.org
Psychotropic drug–related weight gain (PDWG) is a common occurrence and is highly
associated with non-initiation, discontinuation, and dissatisfaction with psychiatric drugs …

[HTML][HTML] Novel compounds in the treatment of schizophrenia—a selective review

EM Tsapakis, K Diakaki, A Miliaras, KN Fountoulakis - Brain Sciences, 2023 - mdpi.com
Schizophrenia is a chronic neuropsychiatric syndrome that significantly impacts daily
function and quality of life. All of the available guidelines suggest a combined treatment …

The role of ketamine in the treatment of bipolar depression: a sco** review

MY Jawad, S Qasim, M Ni, Z Guo, JD Di Vincenzo… - Brain Sciences, 2023 - mdpi.com
Bipolar depression remains a clinical challenge with a quarter of patients failing to respond
to initial conventional treatments. Although ketamine has been extensively studied in …

Efficacy and safety of lumateperone for bipolar depression and schizophrenia: a systematic review and meta-analysis

H Peng, K Yan, S Liu, X Li, X Wang… - International Journal …, 2024 - academic.oup.com
This study aimed to evaluate the efficacy and safety of lumateperone in treating bipolar
disorder and schizophrenia. A comprehensive literature search was conducted across …

Adverse event signal mining and severe adverse event influencing factor analysis of Lumateperone based on FAERS database

Y Zhang, C Zhou, Y Liu, Y Hao, J Wang… - Frontiers in …, 2024 - frontiersin.org
Background Lumateperone has been approved by the Food and Drug Administration (FDA)
for the treatment of schizophrenia in adults since 2019, however, there is still a lack of data …

Post-marketing safety concerns with lumateperone: a pharmacovigilance analysis based on the FDA adverse event reporting system (FAERS) database

D Zhao, W Zhang, Y Liu, Z Yan - Frontiers in Pharmacology, 2024 - frontiersin.org
Objective Lumateperone, a novel antipsychotic drug that was granted by the Food and Drug
Administration (FDA) approval in December 2019, remains insufficiently explored for its …

[HTML][HTML] Pharmacological Treatments of Negative Symptoms in Schizophrenia—An Update

EM Tsapakis, M Treiber, C Mitkani, Z Drakaki… - Journal of Clinical …, 2024 - mdpi.com
Schizophrenia is a chronic psychotic disorder comprising positive symptoms, negative
symptoms, and cognitive deficits. Negative symptoms are associated with stigma, worse …

Lumateperone: A Truly Innovative Antipsychotic Medication?

T DePietro - American Journal of Psychiatry Residents' Journal, 2023 - psychiatryonline.org
Lumateperone (Caplyta, Intra-Cellular Therapies) is a new antipsychotic medication,
approved by the Food and Drug Administration (FDA) in 2019 for adults with schizophrenia …

[PDF][PDF] Unlocking the potential of lumateperone and novel anti-psychotics for schizophrenia

SR Ahmad, M Zeyaullah, AM AlShahrani, MS Khan… - 2025 - bi.tbzmed.ac.ir
Schizophrenia is a devastating chronic mental health illness which includes a complex set of
symptoms like hallucination, illusion and delusion, and to manage, lifelong antipsychotic …

Acute Suicidal Ideation in the Context of Esketamine Maintenance Therapy

F Bell - American Journal of Psychiatry Residents' Journal, 2023 - psychiatryonline.org
Ketamine is an N-methyl-d-aspartate receptor antagonist that is emerging as an effective,
rapid-acting antidepressant for patients with treatment-resistant depression (1–3). Ketamine …