Single-cell transcriptomics has broadened our understanding of cellular diversity and gene
expression dynamics in healthy and diseased tissues. Recently, spatial transcriptomics has …

Since the advent of single-cell RNA sequencing (scRNA-seq) methodology, single-cell
analysis has become a powerful tool for exploration of cellular networks and dysregulated …

Recent advances in single-cell immune profiling have enabled the simultaneous
measurement of transcriptome and T cell receptor (TCR) sequences, offering great potential …

The rapid adoption of single-cell technologies has created an opportunity to build single-cell
'atlases' integrating diverse datasets across many laboratories. Such atlases can serve as a …

The gastrointestinal tract is a multi-organ system crucial for efficient nutrient uptake and
barrier immunity. Advances in genomics and a surge in gastrointestinal diseases, has …

Self-supervised learning (SSL) has emerged as a powerful method for extracting meaningful
representations from vast, unlabelled datasets, transforming computer vision and natural …

Introduction Ageing in the human bone marrow is associated with immune function decline
that results in the elderly being vulnerable to illnesses. A comprehensive healthy bone …

Early characterization of drug targets associated with disease can greatly reduce clinical
failures attributed to lack of safety or efficacy. As single-cell RNA sequencing (scRNA-seq) of …

Single cell computational analysis has emerged as a powerful tool in the field of oncology,
enabling researchers to decipher the complex cellular heterogeneity that characterizes …

Cell state transitions are fundamental in biology, determining how cells respond to
environmental stimuli and adapt to diseases and treatments. Cell surface-based sensing of …