Transition-Metal-Catalyzed, Coordination-Assisted Functionalization of Nonactivated C(sp3)–H Bonds
Transition-metal-catalyzed, coordination-assisted C (sp3)–H functionalization has
revolutionized synthetic planning over the past few decades as the use of these directing …
revolutionized synthetic planning over the past few decades as the use of these directing …
Bidentate directing groups: an efficient tool in C–H bond functionalization chemistry for the expedient construction of C–C bonds
S Rej, Y Ano, N Chatani - Chemical reviews, 2020 - ACS Publications
During the past decades, synthetic organic chemistry discovered that directing group
assisted C–H activation is a key tool for the expedient and siteselective construction of C–C …
assisted C–H activation is a key tool for the expedient and siteselective construction of C–C …
Palladium-catalyzed transformations of alkyl C–H bonds
This Review summarizes the advancements in Pd-catalyzed C (sp3)–H activation via
various redox manifolds, including Pd (0)/Pd (II), Pd (II)/Pd (IV), and Pd (II)/Pd (0). While few …
various redox manifolds, including Pd (0)/Pd (II), Pd (II)/Pd (IV), and Pd (II)/Pd (0). While few …
Transition metal-catalyzed C–H bond functionalizations by the use of diverse directing groups
Z Chen, B Wang, J Zhang, W Yu, Z Liu… - Organic Chemistry …, 2015 - pubs.rsc.org
Transition metal-catalyzed direct functionalization of C–H bonds is one of the key emerging
strategies that is currently attracting tremendous attention with the aim to provide alternative …
strategies that is currently attracting tremendous attention with the aim to provide alternative …
Computational studies of carboxylate-assisted C–H activation and functionalization at group 8–10 transition metal centers
Computational studies on carboxylate-assisted C–H activation and functionalization at
group 8–10 transition metal centers are reviewed. This Review is organized by metal and …
group 8–10 transition metal centers are reviewed. This Review is organized by metal and …
Overcoming the Limitations of γ-and δ-C–H Arylation of Amines through Ligand Development
L, X-Type transient directing groups (TDGs) based on a reversible imine linkage have
emerged as broadly useful tools for C–H activation of ketones and free amines. However …
emerged as broadly useful tools for C–H activation of ketones and free amines. However …
Ligand-Enabled Pd(II)-Catalyzed β-Methylene C(sp3)–H Arylation of Free Aliphatic Acids
Ligand development has enabled rapid advances in Pd (II)-catalyzed β-methyl C (sp3)–H
activation of free carboxylic acids. However, there are only a handful of reports of free-acid …
activation of free carboxylic acids. However, there are only a handful of reports of free-acid …
Reusable directing groups [8-aminoquinoline, picolinamide, sulfoximine] in C (sp3)–H bond activation: present and future
This report briefly discusses the reusable directing group assisted functionalization of
unactivated remote alkyl C–H bonds and their synthetic potential in organic chemistry. The …
unactivated remote alkyl C–H bonds and their synthetic potential in organic chemistry. The …
On the Mechanism and Selectivity of Palladium-Catalyzed C(sp3)–H Arylation of Pyrrolidines and Piperidines at Unactivated C4 Positions: Discovery of an Improved …
Directed C–H functionalization is a powerful means to functionalize otherwise unreactive C–
H bonds, for which aminoquinoline amides provide a powerful and frequently used directing …
H bonds, for which aminoquinoline amides provide a powerful and frequently used directing …
Palladium(II)‐Catalyzed Enantioselective Arylation of Unbiased Methylene C(sp3)−H Bonds Enabled by a 2‐Pyridinylisopropyl Auxiliary and Chiral Phosphoric Acids
SY Yan, YQ Han, QJ Yao, XL Nie… - Angewandte Chemie …, 2018 - Wiley Online Library
Enantioselective functionalizations of unbiased methylene C (sp3)− H bonds of linear
systems by metal insertion are intrinsically challenging and remain a largely unsolved …
systems by metal insertion are intrinsically challenging and remain a largely unsolved …