Role of advanced neuroimaging, fluid biomarkers and genetic testing in the assessment of sport-related concussion: a systematic review

M McCrea, T Meier, D Huber, A Ptito… - British journal of sports …, 2017 - bjsm.bmj.com
Objective To conduct a systematic review of published literature on advanced neuroimaging,
fluid biomarkers and genetic testing in the assessment of sport-related concussion (SRC) …

The molecular pathophysiology of concussive brain injury–an update

G Barkhoudarian, DA Hovda… - Physical Medicine and …, 2016 - pmr.theclinics.com
Concussion (mild traumatic brain injury [TBI]), particularly with organized sports, has come to
the forefront of popular culture. Affecting about 1.6 million to 3.8 million athletes a year, its …

Rapid optofluidic detection of biomarkers for traumatic brain injury via surface-enhanced Raman spectroscopy

JJS Rickard, V Di-Pietro, DJ Smith, DJ Davies… - Nature biomedical …, 2020 - nature.com
Current technologies for the point-of-care diagnosis of traumatic brain injury (TBI) lack
sensitivity, require specialist handling or involve complicated and costly procedures. Here …

The biological significance and clinical utility of emerging blood biomarkers for traumatic brain injury

ME Huibregtse, JJ Bazarian, SR Shultz… - … & Biobehavioral Reviews, 2021 - Elsevier
Abstract HUIBREGTSE, ME, Bazarian, JJ, Shultz, SR, and Kawata K. The biological
significance and clinical utility of emerging blood biomarkers for traumatic brain injury …

Advanced neuroimaging in traumatic brain injury: an overview

LGF Smith, E Milliron, ML Ho, HH Hu, J Rusin… - Neurosurgical …, 2019 - thejns.org
Traumatic brain injury (TBI) is a common condition with many potential acute and chronic
neurological consequences. Standard initial radiographic evaluation includes noncontrast …

Attenuated traumatic axonal injury and improved functional outcome after traumatic brain injury in mice lacking Sarm1

N Henninger, J Bouley, EM Sikoglu, J An, CM Moore… - Brain, 2016 - academic.oup.com
Axonal degeneration is a critical, early event in many acute and chronic neurological
disorders. It has been consistently observed after traumatic brain injury, but whether axon …

Concussion as a multi-scale complex system: an interdisciplinary synthesis of current knowledge

ES Kenzie, EL Parks, ED Bigler, MM Lim… - Frontiers in …, 2017 - frontiersin.org
Traumatic brain injury (TBI) has been called “the most complicated disease of the most
complex organ of the body” and is an increasingly high-profile public health issue. Many …

The potential for animal models to provide insight into mild traumatic brain injury: translational challenges and strategies

SR Shultz, SJ McDonald, CV Haar, A Meconi… - Neuroscience & …, 2017 - Elsevier
Mild traumatic brain injury (mTBI) is a common health problem. There is tremendous
variability and heterogeneity in human mTBI, including mechanisms of injury, biomechanical …

Neuroepidemiology of traumatic brain injury

AJ Gardner, R Zafonte - Handbook of clinical neurology, 2016 - Elsevier
Traumatic brain injury (TBI) is a significant public-health concern. TBI is defined as an acute
brain injury resulting from mechanical energy to the head from external physical forces …

Neurochemical cascade of concussion

MP MacFarlane, TC Glenn - Brain injury, 2015 - Taylor & Francis
Primary objective: The aim of this literature review was to systematically describe the
sequential metabolic changes that occur following concussive injury, as well as identify and …