Glucocorticoids are a backbone of treatment for multiple myeloma in both the upfront and
relapsed/refractory setting. While glucocorticoids have single agent activity in multiple …

Eye involvement represents a common finding in patients with systemic autoimmune
diseases, particularly rheumatoid arthritis, Sjogren syndrome, seronegative …

Dexamethasone (Dex) is a synthetic glucocorticoid that has anti-inflammatory and
immunosuppressant effects and is used in several conditions such as asthma and severe …

Objective To assess the outcomes of several rodent animal models for studying tooth
extraction-related medication-related osteonecrosis of the jaw (MRONJ). Design After a …

Corticosteroids constitute a first-line therapy for adults and children suffering from
nonmalignant immune-mediated hematologic diseases. However, high disease relapse …

Background Patients with autoimmune blistering diseases (AIBDs) are often exposed to
chronic glucocorticoid (GC) treatment with many side effects. Glucocorticoid‐induced …

Glucocorticoids are the mainstay of treatment for GCA. Patients often require long-term
treatment that may be associated with numerous adverse effects, depending on the dose …

Glucocorticoid-induced osteoporosis (GIOP) represents the foremost cause of secondary
osteoporosis and fragility fractures. Novel therapeutic strategies for GIOP are needed, with …

On-target, off-tissue toxicity limits the systemic use of drugs that would otherwise reduce
symptoms or reverse the damage of arthritic diseases, leaving millions of patients in pain …

Background Chronic wounds (eg diabetic foot ulcers) reduce the quality of life, yet
treatments remain limited. Glucocorticoids (activated by the enzyme 11β-hydroxysteroid …