Lipid nanoparticles─ from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement

R Tenchov, R Bird, AE Curtze, Q Zhou - ACS nano, 2021 - ACS Publications
Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …

Distinguishing features of current COVID-19 vaccines: knowns and unknowns of antigen presentation and modes of action

FX Heinz, K Stiasny - npj Vaccines, 2021 - nature.com
COVID-19 vaccines were developed with an unprecedented pace since the beginning of the
pandemic. Several of them have reached market authorization and mass production …

Impact of COVID-19 pandemic on socio-economic, energy-environment and transport sector globally and sustainable development goal (SDG)

S Nundy, A Ghosh, A Mesloub, GA Albaqawy… - Journal of Cleaner …, 2021 - Elsevier
Abstract The United Nation's Sustainable Development Goals (SDGs) want to have a
peaceful world where human life will be in a safe, healthy, sustainable environment without …

Potential factors influencing COVID-19 vaccine acceptance and hesitancy: A systematic review

DN Roy, M Biswas, E Islam, MS Azam - PloS one, 2022 - journals.plos.org
Background and aims Although vaccines are considered the most effective and fundamental
therapeutic tools for consistently preventing the COVID-19 disease, worldwide vaccine …

Cutaneous findings following COVID‐19 vaccination: review of world literature and own experience

T Gambichler, S Boms, L Susok… - Journal of the …, 2022 - Wiley Online Library
There is growing evidence that not only the novel coronavirus disease (COVID‐19) but also
the COVID‐19 vaccines can cause a variety of skin reactions. In this review article, we …

PEGylated lipid nanoparticle formulations: immunological safety and efficiency perspective

R Tenchov, JM Sasso, QA Zhou - Bioconjugate chemistry, 2023 - ACS Publications
Lipid nanoparticles (LNPs) have been recognized as efficient vehicles to transport a large
variety of therapeutics. Currently in the spotlight as important constituents of the COVID-19 …

Glycoconjugates: synthesis, functional studies, and therapeutic developments

SS Shivatare, VS Shivatare, CH Wong - Chemical reviews, 2022 - ACS Publications
Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …

COVID-19: unmasking emerging SARS-CoV-2 variants, vaccines and therapeutic strategies

R Raman, KJ Patel, K Ranjan - Biomolecules, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of
the coronavirus disease 2019 (COVID-19) pandemic, which has been a topic of major …

Viral vector‐based gene therapies in the clinic

Z Zhao, AC Anselmo, S Mitragotri - … & translational medicine, 2022 - Wiley Online Library
Gene therapies are currently one of the most investigated therapeutic modalities in both the
preclinical and clinical settings and have shown promise in treating a diverse spectrum of …

Progress and challenges in targeting the SARS-CoV-2 papain-like protease

H Tan, Y Hu, P Jadhav, B Tan… - Journal of medicinal …, 2022 - ACS Publications
SARS-CoV-2 is the causative agent of the COVID-19 pandemic. The approval of vaccines
and small-molecule antivirals is vital in combating the pandemic. The viral polymerase …