A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD)

J Peng, M Fan, C An, F Ni, W Huang… - Basic & clinical …, 2022 - Wiley Online Library
Cannabidiol (CBD) is an abundant non‐psychoactive phytocannabinoid in cannabis
extracts which has high affinity on a series of receptors, including Type 1 cannabinoid …

Neural circuits for emotion

M Malezieux, AS Klein, N Gogolla - Annual review of …, 2023 - annualreviews.org
Emotions are fundamental to our experience and behavior, affecting and motivating all
aspects of our lives. Scientists of various disciplines have been fascinated by emotions for …

Brain-wide map** reveals that engrams for a single memory are distributed across multiple brain regions

DS Roy, YG Park, ME Kim, Y Zhang, SK Ogawa… - Nature …, 2022 - nature.com
Neuronal ensembles that hold specific memory (memory engrams) have been identified in
the hippocampus, amygdala, or cortex. However, it has been hypothesized that engrams of …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

The emergence and influence of internal states

SW Flavell, N Gogolla, M Lovett-Barron, M Zelikowsky - Neuron, 2022 - cell.com
Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

A paradigm shift in translational psychiatry through rodent neuroethology

Y Shemesh, A Chen - Molecular psychiatry, 2023 - nature.com
Mental disorders are a significant cause of disability worldwide. They profoundly affect
individuals' well-being and impose a substantial financial burden on societies and …

Emotional expressions reconsidered: Challenges to inferring emotion from human facial movements

LF Barrett, R Adolphs, S Marsella… - … science in the …, 2019 - journals.sagepub.com
It is commonly assumed that a person's emotional state can be readily inferred from his or
her facial movements, typically called emotional expressions or facial expressions. This …

The central nucleus of the amygdala and the construction of defensive modes across the threat-imminence continuum

JM Moscarello, MA Penzo - Nature Neuroscience, 2022 - nature.com
In nature, animals display defensive behaviors that reflect the spatiotemporal distance of
threats. Laboratory-based paradigms that elicit specific defensive responses in rodents have …

The theory of constructed emotion: an active inference account of interoception and categorization

LF Barrett - Social cognitive and affective neuroscience, 2017 - academic.oup.com
The science of emotion has been using folk psychology categories derived from philosophy
to search for the brain basis of emotion. The last two decades of neuroscience research …

Fear balance is maintained by bodily feedback to the insular cortex in mice

AS Klein, N Dolensek, C Weiand, N Gogolla - Science, 2021 - science.org
How does the brain maintain fear within an adaptive range? We found that the insular cortex
acts as a state-dependent regulator of fear that is necessary to establish an equilibrium …