[HTML][HTML] Recent advances in electrochemical biosensors: Applications, challenges, and future scope

A Singh, A Sharma, A Ahmed, AK Sundramoorthy… - Biosensors, 2021‏ - mdpi.com
The electrochemical biosensors are a class of biosensors which convert biological
information such as analyte concentration that is a biological recognition element …

Biosensors and their applications–A review

P Mehrotra - Journal of oral biology and craniofacial research, 2016‏ - Elsevier
The various types of biosensors such as enzyme-based, tissue-based, immunosensors,
DNA biosensors, thermal and piezoelectric biosensors have been deliberated here to …

Clarifying lysosomal storage diseases

ML Schultz, L Tecedor, M Chang, BL Davidson - Trends in neurosciences, 2011‏ - cell.com
Lysosomal storage diseases (LSDs) are a class of metabolic disorders caused by mutations
in proteins critical for lysosomal function. Such proteins include lysosomal enzymes …

Regulation of V-ATPase activity and organelle pH by phosphatidylinositol phosphate lipids

S Banerjee, PM Kane - Frontiers in cell and developmental biology, 2020‏ - frontiersin.org
Luminal pH and the distinctive distribution of phosphatidylinositol phosphate (PIP) lipids are
central identifying features of organelles in all eukaryotic cells that are also critical for …

[HTML][HTML] Flip** the script: Advances in understanding how and why P4-ATPases flip lipid across membranes

AC Norris, AJ Mansueto, M Jimenez… - … et Biophysica Acta (BBA …, 2024‏ - Elsevier
Abstract Type IV P-type ATPases (P4-ATPases) are a family of transmembrane enzymes that
translocate lipid substrates from the outer to the inner leaflet of biological membranes and …

Proton transport and pH control in fungi

PM Kane - Yeast membrane transport, 2016‏ - Springer
Despite diverse and changing extracellular environments, fungi maintain a relatively
constant cytosolic pH and numerous organelles of distinct lumenal pH. Key players in fungal …

Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pHc in Saccharomyces cerevisiae

R Orij, ML Urbanus, FJ Vizeacoumar, G Giaever… - Genome biology, 2012‏ - Springer
Background Because protonation affects the properties of almost all molecules in cells,
cytosolic pH (pH c) is usually assumed to be constant. In the model organism yeast …

Coupled synthesis and translocation restrains polyphosphate to acidocalcisome-like vacuoles and prevents its toxicity

R Gerasimaitė, S Sharma, Y Desfougeres… - Journal of cell …, 2014‏ - journals.biologists.com
Eukaryotes contain inorganic polyphosphate (polyP) and acidocalcisomes, which sequester
polyP and store amino acids and divalent cations. Why polyP is sequestered in dedicated …

An inside job: how endosomal Na+/H+ exchangers link to autism and neurological disease

KC Kondapalli, H Prasad, R Rao - Frontiers in cellular neuroscience, 2014‏ - frontiersin.org
Autism imposes a major impediment to childhood development and a huge emotional and
financial burden on society. In recent years, there has been rapidly accumulating genetic …

The proteolytic landscape of the yeast vacuole

KA Hecht, AF O'Donnell, JL Brodsky - Cellular logistics, 2014‏ - Taylor & Francis
The vacuole in the yeast Saccharomyces cerevisiae plays a number of essential roles, and
to provide some of these required functions the vacuole harbors at least seven distinct …