Fuchs endothelial corneal dystrophy (FECD) is the most common primary corneal
endothelial dystrophy and the leading indication for corneal transplantation worldwide …

The cornea is exquisitely designed to protect the eye while transmitting and focusing
incoming light. Precise control of corneal hydration by the endothelial cell layer that lines the …

The state of the art therapy for treating corneal endothelial disease is transplantation.
Advances in the reproducibility and accessibility of surgical techniques are increasing the …

We aimed to construct a biodegradable transparent scaffold for culturing corneal endothelial
cells by incorporating chitosan nanoparticles (CSNPs) into chitosan/polycaprolactone (PCL) …

Corneal endothelial diseases are leading indications for corneal transplantations. With
significant advancement in medical science and surgical techniques, corneal transplant …

The corneal endothelium is the posterior monolayer of cells that are responsible for
maintaining overall transparency of the avascular corneal tissue via pump function. These …

The corneal endothelium located on the posterior corneal surface is responsible for
regulating stromal hydration. This is contributed by a monolayer of corneal endothelial cells …

The limited availability of a healthy donor cornea and the incidence of allograft failure led
researchers to seek other corneal substitutes via tissue engineering. Exploring the trend of …

Corneal transplantation is the only treatment for corneal endothelial blindness. However,
there is an urgent need to find substitutes for corneal endothelium grafts due to the global …

The corneal endothelium plays a key role in maintaining corneal transparency. Its
dysfunction is currently treated with penetrating or lamellar keratoplasty. Advanced cell …