Preeclampsia is a life-threatening pregnancy-associated cardiovascular disorder
characterized by hypertension and proteinuria at 20 weeks of gestation. Though its exact …

Preeclampsia is a devastating medical complication of pregnancy that can lead to significant
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …

Fetal growth restriction (FGR) is defined as the failure of the fetus to meet its growth potential
due to a pathological factor, most commonly placental dysfunction. Worldwide, FGR is a …

Preeclampsia continues to afflict 5% to 8% of all pregnancies throughout the world and is
associated with significant morbidity and mortality to the mother and the fetus. Although the …

Hypertensive disorders of pregnancy increase the risk of adverse maternal and fetal
outcomes. In 2018, the Japanese classification of hypertensive disorders of pregnancy was …

Placental dysfunction underlies a spectrum of perinatal pathologies, including preeclampsia
and fetal growth restriction. Angiogenesis-related factors, including sFlt-1 (soluble fms-like …

Pregnancy-induced hypertension (PIH) complicates 6–10% of pregnancies. It is defined as
systolic blood pressure (SBP)> 140 mmHg and diastolic blood pressure (DBP)> 90 mmHg. It …

Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles
originating from different cell compartments. EVs participate in many essential physiological …

Preeclampsia is a leading cause of pregnancy-related morbidity and mortality in the United
States. In the past 30 years, a large amount of research has been performed to investigate …

The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …