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Polysialic acid: Biosynthesis, novel functions and applications
KJ Colley, K Kitajima, C Sato - Critical reviews in biochemistry and …, 2014 - Taylor & Francis
As an anti-adhesive, a reservoir for key biological molecules, and a modulator of signaling,
polysialic acid (polySia) is critical for nervous system development and maintenance …
polysialic acid (polySia) is critical for nervous system development and maintenance …
High-throughput and high-efficiency sample preparation for single-cell proteomics using a nested nanowell chip
Global quantification of protein abundances in single cells could provide direct information
on cellular phenotypes and complement transcriptomics measurements. However, single …
on cellular phenotypes and complement transcriptomics measurements. However, single …
Advancement of sialyltransferase inhibitors: therapeutic challenges and opportunities
R Szabo, D Skropeta - Medicinal Research Reviews, 2017 - Wiley Online Library
Hypersialylation of tumor cell surface proteins along with a marked upregulation of
sialyltransferase (ST) activity is a well‐established hallmark of cancer. Due to the critical role …
sialyltransferase (ST) activity is a well‐established hallmark of cancer. Due to the critical role …
Engineering of complex protein sialylation in plants
S Kallolimath, A Castilho, R Strasser… - Proceedings of the …, 2016 - pnas.org
Sialic acids (Sias) are abundant terminal modifications of protein-linked glycans. A unique
feature of Sia, compared with other monosaccharides, is the formation of linear homo …
feature of Sia, compared with other monosaccharides, is the formation of linear homo …
Polysialic acid is a cellular receptor for human adenovirus 52
A Lenman, AM Liaci, Y Liu, L Frängsmyr… - Proceedings of the …, 2018 - pnas.org
Human adenovirus 52 (HAdV-52) is one of only three known HAdVs equipped with both a
long and a short fiber protein. While the long fiber binds to the coxsackie and adenovirus …
long and a short fiber protein. While the long fiber binds to the coxsackie and adenovirus …
[HTML][HTML] Characterization of distinct populations of carcinoma-associated fibroblasts from non–small cell lung carcinoma reveals a role for ST8SIA2 in cancer cell …
Carcinoma-associated fibroblasts (CAFs) are abundant stromal cells in tumor
microenvironment that are critically involved in cancer progression. Contrasting reports have …
microenvironment that are critically involved in cancer progression. Contrasting reports have …
Polysialic acid is present in mammalian semen as a post-translational modification of the neural cell adhesion molecule NCAM and the polysialyltransferase ST8SiaII
P Simon, S Bäumner, O Busch, R Röhrich… - Journal of Biological …, 2013 - jbc.org
Fertilization in animals is a complex sequence of several biochemical events beginning with
the insemination into the female reproductive tract and, finally, leading to embryogenesis …
the insemination into the female reproductive tract and, finally, leading to embryogenesis …
[HTML][HTML] Polysialic acid interacts with lactoferrin and supports its activity to inhibit the release of neutrophil extracellular traps
A Kühnle, R Veelken, CE Galuska, M Saftenberger… - Carbohydrate …, 2019 - Elsevier
Polysialic acid (polySia) is a linear carbohydrate polymer consisting of N-acetylneuraminic
acid residues and is involved in several physiological processes. In the present study, we …
acid residues and is involved in several physiological processes. In the present study, we …
Changes in polysialic acid expression on myeloid cells during differentiation and recruitment to sites of inflammation: role in phagocytosis
NM Stamatos, L Zhang, A Jokilammi, J Finne… - …, 2014 - academic.oup.com
Polysialic acid (polySia) is a unique linear homopolymer of α2, 8-linked sialic acid that has
been studied extensively as a posttranslational modification of neural cell adhesion …
been studied extensively as a posttranslational modification of neural cell adhesion …
Neuroimmunomodulatory properties of polysialic acid
L Gretenkort, H Thiesler, H Hildebrandt - Glycoconjugate journal, 2023 - Springer
Polymeric sialic acid (polysialic acid, polySia) is a remarkable posttranslational modification
of only few select proteins. The major, and most prominent polySia protein carrier is the …
of only few select proteins. The major, and most prominent polySia protein carrier is the …