The microbiome and gynaecological cancer development, prevention and therapy

P Łaniewski, ZE Ilhan, MM Herbst-Kralovetz - Nature Reviews Urology, 2020 - nature.com
The female reproductive tract (FRT), similar to other mucosal sites, harbours a site-specific
microbiome, which has an essential role in maintaining health and homeostasis. In the …

Genome organization and genomics in Chlamydia: whole genome sequencing increases understanding of chlamydial virulence, evolution, and phylogeny

LDW Luu, V Kasimov, S Phillips, GSA Myers… - Frontiers in cellular …, 2023 - frontiersin.org
The genus Chlamydia contains important obligate intracellular bacterial pathogens to
humans and animals, including C. trachomatis and C. pneumoniae. Since 1998, when the …

Role of the microbiome in oral cancer occurrence, progression and therapy

Z Li, Y Liu, L Zhang - Microbial Pathogenesis, 2022 - Elsevier
The oral cavity, like other digestive or mucosal sites, contains a site-specific microbiome that
plays a significant role in maintaining health and homeostasis. Strictly speaking, the …

Organoids of the female reproductive tract

C Chumduri, MY Turco - Journal of molecular medicine, 2021 - Springer
Healthy functioning of the female reproductive tract (FRT) depends on balanced and
dynamic regulation by hormones during the menstrual cycle, pregnancy and childbirth. The …

The microbiome and cancer: creating friendly neighborhoods and removing the foes within

S Parida, D Sharma - Cancer Research, 2021 - aacrjournals.org
The human body is colonized by the microbial cells that are estimated to be as abundant as
human cells, yet their genome is roughly 100 times the human genome, providing …

[HTML][HTML] The vaginal microbiome: IV. The role of vaginal microbiome in reproduction and in gynecologic cancers

G Ventolini, P Vieira-Baptista, F De Seta… - Journal of Lower …, 2022 - journals.lww.com
Objective This series of articles, titled The Vaginal Microbiome (VMB), written on behalf of
the International Society for the Study of Vulvovaginal Disease, aims to summarize the …

The cancer microbiota: EMT and inflammation as shared molecular mechanisms associated with plasticity and progression

D Vergara, P Simeone, M Damato, M Maffia… - Journal of …, 2019 - Wiley Online Library
With the advent of novel molecular platforms for high‐throughput/next‐generation
sequencing, the communities of commensal and pathogenic microorganisms that inhabit the …

Gynecological cancers and Microbiota dynamics: insights into Pathogenesis and Therapy

G Cocomazzi, L Del Pup, V Contu, G Maggio… - International Journal of …, 2024 - mdpi.com
In recent years, the relationship between the microbiota and various aspects of health has
become a focal point of scientific investigation. Although the most studied microbiota …

Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection

RK Gurumurthy, S Koster, N Kumar, TF Meyer… - Nature …, 2022 - nature.com
The cervix is the gateway to the upper female reproductive tract, connecting the uterus and
vagina. It plays crucial roles in fertility and pregnancy maintenance from onset until delivery …

An endometrial organoid model of interactions between Chlamydia and epithelial and immune cells

L Dolat, RH Valdivia - Journal of cell science, 2021 - journals.biologists.com
Our understanding of how the obligate intracellular bacterial pathogen Chlamydia
trachomatis reprograms the function of infected cells in the upper genital tract is largely …